How effective is the spironolactone for hair loss?
The use of spironolactone for hair loss can be somewhat effective, but only when the drug is prepared in a 5% cream solution. Dosage that one would have to have in the form of pills would significantly increase the risk of side effects such as hyperkalaemia. This drug is usually used to treat patients who have hyperaldosteronism, low potassium or swelling.
Spironolactone is a diuretic and has a long list of side effects that accompany it. It can cause drowsiness, nausea, rashes, headaches and jaundice. There are other possible side effects, which is the use of standard spironolactone for problematic hair loss. However, it has been found that spironolactone is an anti-Androgen, which means that it could actually reduce hair loss. Androgens are hormones that are directly responsible for the level of hair growth. There are many different types of androgens and scientists have found that when androgens are present around the hair follicles, the follicles were weaker. Finally IdenzabAvil androgen dihydrotestosterone (DHT) as the one responsible for the baldness of the male pattern and one that is bound to hair loss. Anti-androgens must be focused on specific androgens to be effective. Spironolactone for hair loss acts as a treatment because it is identified as anti-androgen.
The only thing that prevents spironolactone from effective treatment of hair loss is the fact that dosing a pill that is required to significantly reduce DHT levels would cause adverse effects. The solution to this problem was the use of the cream version. The drug concentration is only 5%in preparation, referred to as local spironolactone and has been shown to create local effects in the amount of DHT present in subjects.
Although the cream can be used to potentially stop hair loss, treatment cannot be used to cause hair growth.Hair falling up can doctors to combine it with a more efficient anti-Androgen such as finasteride. Spironolactone efficacy may vary from person to person and it is advisable to talk to a doctor before subjugating any treatment. However, preliminary results have found any side effects from the use of local spironolactone cream.