What Are Progesterone Suppositories?

Progesterone suppositories, indications are for the treatment of menstrual disorders such as amenorrhea and functional uterine bleeding, luteal dysfunction, threatened abortion and habitual abortion (caused by luteal deficiency), and premenstrual tension syndrome.

Progesterone suppositories, indications are for the treatment of menstrual disorders such as amenorrhea and functional uterine bleeding, luteal dysfunction, threatened abortion and habitual abortion (caused by luteal deficiency), and premenstrual tension syndrome.

Drug Name

Progesterone suppository

Drug type

Prescription drugs, external drugs

Use classification

Progestins

Progesterone suppository drug name

[General name] progesterone suppository

[English name] Progesterone Suppositories

Chinese Phonetic Alphabet Huang Ti Tong Shuan

Progesterone suppository category

Chemical Drugs & Biological Products >> Metabolic and Endocrine System Drugs >> Sex Hormones >> Progestins

Progesterone suppository ingredients

Progesterone.

Progesterone suppository traits

This product is a milky white to pale yellow thunder suppository.

Progesterone suppository indications

For menstrual disorders, such as amenorrhea and functional uterine bleeding, luteal dysfunction, threatened abortion and habitual abortion (caused by luteal insufficiency), premenstrual tension syndrome.

Progesterone suppository specifications

25mg.

Progesterone suppository dosage

Vaginal administration. 1 capsule at a time, 1 or 2 times a day. Put it in the posterior fornix of the vagina and lie in bed for 15-30 minutes. The course of treatment is handled by the physician according to different indications.

Adverse effects of progesterone suppository

Occasionally nausea, dizziness and headache, burnout, urticaria, breast swelling and so on.

Progesterone suppository

1. Disable patients with severe liver injury (make the symptoms worse).
2. Prohibited during acute vaginal inflammation and bleeding.

Progesterone suppositories

1. Patients with kidney disease, heart disease, edema, and hypertension should be used with caution.
2. The existence of progesterone deficiency in premenstrual tension is inconclusive, so the use of progesterone treatment is still controversial.
3. Patients other than threatened abortion should be thoroughly checked before administration to determine that they are luteal dysfunction before re-use.
4. At present, natural progesterone is commonly used to treat threatened abortion and habitual abortion. Synthetic progesterone can not be used as a fetal medicine because of fetal teratogenicity problems.
5. Long-term medication should pay attention to check liver function, pay special attention to breast examination.

Progesterone suppositories for pregnant and lactating women

Use with caution within 4 months of pregnancy to prevent miscarriage.

Progesterone suppository drug interactions

still uncertain.

Progesterone suppository drug overdose

Long-term application can cause abnormal liver function, edema, weight gain, endometrial atrophy, decreased menstrual volume or amenorrhea, and prone to vaginal candida infection.

Progesterone suppository pharmacology and toxicology

This product is a progestin drug, which has the general effect of progestin. The endometrium secretion period can be changed at the later stage of the menstrual cycle, which provides favorable conditions for the implantation of pregnant eggs. After the fertilized eggs are implanted, the placenta is formed, which can reduce the excitability of the pregnant uterus and allow the fetus to grow safely. When combined with estrogen, it can promote breast development and prepare for milk production. This product can inhibit the release of luteinizing hormone from the anterior pituitary gland through negative feedback to the hypothalamus, prevent follicles from developing and mature, and inhibit the ovulation process of the ovary.

Progesterone suppository pharmacokinetics

This product is quickly absorbed through the vaginal mucosa, and the blood concentration reaches a peak after 2 to 6 hours. Metabolized in the liver, about 12% is metabolized to pregnanediol, and the metabolites are combined with glucuronic acid and excreted with urine.

Progesterone suppository storage

Shaded, sealed and stored in a cool place.

Progesterone suppository packaging

25mg × 10 capsules.

Progesterone suppository

3 years ^[1]