What Are the Most Common Ofloxacin Side Effects?

Levofloxacin hydrochloride is suitable for urogenital infections caused by sensitive bacteria, including simple, complex urinary tract infections, bacterial prostatitis, Neisseria gonorrhoeae urethritis, or cervicitis (including those caused by enzyme-producing strains). Respiratory tract infections, including acute attacks of bronchial infections and lung infections caused by sensitive Gram-negative bacilli. Gastrointestinal infections are caused by Shigella, Salmonella, Enterotoxigenic E. coli, Aeromonas hydrophila, Vibrio parahaemolyticus, and the like. It can also treat systemic infections such as typhoid fever, bone and joint infections, skin and soft tissue infections, and sepsis.

Levofloxacin Hydrochloride

Left hydrochloride

Chinese alias: Levofloxacin hydrochloride; (3S)-(-)-9-fluoro-2,3-dihydro-3-methyl-10- (4-methyl-1-piperazinyl) -7-oxygen -; 7H-pyrido [1,2,3-de]-[1,4] benzoxazine-6-carboxylic acid hydrochloride; levofloxacin · hydrochloride;

English name: Levofloxacin Hydrochloride

English alias: LEVOFLOXACIN HCL; carboxylic acid monohydrochloride; LevofloxacinHydrochloride; (3S) -9-fluoro-3-methyl-10- (4-methylpiperazin-1-yl) -7-oxo-2,3-dihydro-7H- [1 , 4] oxazino [2,3,4-ij] quinoline-6-carboxylic acid hydrochloride:

Molecular formula: C18H21ClFN3O4

Boiling point: 571.5 ° C at 760 mmHg
Flash point: 299.4 ° C
Vapor pressure: 6.7E-14mmHg at 25 ° C

for

This product is suitable for the following mild and moderate infections caused by sensitive bacteria;

Respiratory system infection:

The oral absorption rate is almost 100%. Usual Adult:

1. Bronchial infection, pulmonary infection: 0.2g once, twice a day, or 0.1g once, three times a day, the course of treatment is 7 to 14 days.

2. Acute simple lower urinary tract infection: 0.1g once, 2 times a day, 5 to 7 days of treatment; Complex urinary tract infection: 0.2g once, 2 times a day, or 0.1g, 3 times a day, 10 courses ~ 14th.

3

Symptoms such as nausea, vomiting, abdominal discomfort, diarrhea, lack of appetite, abdominal pain, bloating, neurological symptoms such as insomnia, dizziness, headache, and rashes, itching may occur during medication. Transient liver dysfunction may also occur, such as increased serum aminotransferases and increased serum total bilirubin. The incidence of these adverse reactions was between 0.1% and 5%. Occasionally in the blood

1. Concurrent application with non-steroidal anti-inflammatory analgesics (such as aspirin, ibuprofen, acetaminophen, etc.) may cause convulsions.
2. Concurrent use with oral hypoglycemic agents may cause blood sugar disorders, including hyperglycemia and hypoglycemia.
3. Sometimes nausea, vomiting, abdominal discomfort, diarrhea, abdominal pain, indigestion, etc.
4, sometimes allergic reactions, such as: occasional edema, urticaria, fever, photosensitivity and sometimes rash, itching, erythema and other symptoms;
5. Occasional nervous system reactions: such as tremor, numbness, visual abnormalities, tinnitus, hallucinations, drowsiness, and sometimes symptoms such as insomnia, dizziness, and headache;
6. Kidney: Occasionally urea nitrogen in blood rises.
7, can cause abnormal liver function, such as transient blood aminotransferase increased, serum total bilirubin increased.
8. Sometimes anemia, leukopenia, thrombocytopenia, and eosinophilia increase.
The incidence of the above-mentioned adverse reactions is between 0.1% and 5%, which are generally tolerable, and disappear quickly after the end of the course of treatment. If abnormalities are found, you should observe them, and if necessary, you can stop medication and take appropriate measures.

1. Patients with renal insufficiency should reduce or prolong the interval between administrations, and those with severe renal insufficiency should be used with caution.

2. Patients with a history of central nervous system disease and epilepsy should be used with caution.

3. Quinolones can still cause rare phototoxic reactions (incidence rate <0.1%). Avoid excessive sun exposure and artificial UV rays when receiving this product. Stop photosensitivity or skin damage.

4. If allergies occur, the drug should be discontinued immediately, and the following drugs or methods should be taken according to the specific clinical situation; adrenaline and other rescue measures, including oxygen inhalation, intravenous infusion, antihistamines, corticosteroids, etc.

5. In addition, there are occasional reports of Achilles tendinitis or Achilles tendon rupture after medication. Therefore, if the above symptoms occur, the drug should be stopped and rested immediately. Exercise is strictly prohibited until the symptoms disappear.

6. If taken in excess, the contents of the stomach of the patient should be removed, proper fluid replacement should be maintained, and clinical observation should be performed.

7. Levofloxacin cannot be effectively ruled out by hemodialysis or peritoneal dialysis.

8. Drug Interactions: The simultaneous use of this product with antacids containing magnesium or aluminum, sucralfate, metal cations (such as iron), and multivitamin preparations containing zinc will interfere with the gastrointestinal tract against this product. Absorption, so that the concentration of the drug in each system is significantly reduced. Therefore, the above medicine should be taken at least 2 hours before or after using this product.

Avoid simultaneous use with theophylline. If simultaneous use is needed, the blood concentration of theophylline should be monitored and the dose adjusted accordingly.

When used concurrently with warfarin or its derivatives, the prothrombin time or other coagulation tests should be monitored.

Concurrent application with non-steroidal anti-inflammatory drugs may cause convulsions.

Concurrent use with oral hypoglycemic agents may cause blood sugar disorders, including high blood sugar and hypoglycemia, so the blood glucose concentration should be monitored during the medication process. Once hypoglycemia occurs, this product should be discontinued immediately and given appropriate treatment.