What Is a Subdermal Implant?
Traditional subcutaneous implants contain 2 or 6 flexible tubes. At present, subcutaneous implants only contain 1 flexible EVA tube, which is implanted under the skin on the inside of the upper arm through local anesthesia. Contains progestin, can be used for 3 to 5 years, the effective rate of contraception is as high as 99%, and fertility is restored immediately after removal.
Subcutaneous implant
Right!
- Chinese name
- Subcutaneous implant
- Foreign name
- Subcutaneous implants
- Include
- Contains 2 or 6 flexible tubes
- Nature
- Slow release contraceptive system
- Traditional subcutaneous implants contain 2 or 6 flexible tubes. At present, subcutaneous implants only contain 1 flexible EVA tube, which is implanted under the skin on the inside of the upper arm through local anesthesia. Contains progestin, can be used for 3 to 5 years, the effective rate of contraception is as high as 99%, and fertility is restored immediately after removal.
- However, the disadvantage of subcutaneous implants is that, like all hormonal contraceptives, it may lead to changes in bleeding patterns in women, such as irregular menstruation. [1]
- A slow-release contraceptive system implanted under the skin of women of childbearing age. The current subcutaneous implants all use synthetic progestins, such as L-18-methyl norethisterone or desognolone. According to the properties of polymer carriers, it is divided into two categories: non-biodegradable and biodegradable. The currently used Nopland and Nopland II types, the levonorgestrel silicone rods produced in China, and the two types of norethindrone implants are non-biodegradable subcutaneous implants. Developed by the U.S. Population Council, Nopland is currently the longest and most widely used subcutaneous implant in the world. The dosage form is a silicone rubber tube with a length of 34 mm and a diameter of 2.4 mm. It contains 36 mg of l-norethindrone and is closed at both ends. Within 7 days of menstrual cramps, under strict disinfection conditions, it is generally buried in the forearm and 6 roots are implanted at a time. It exerts contraceptive effect after 24 hours of implantation. The total drug release rate started at 68 micrograms / day, dropped to 40 micrograms / day after 1 year, and 30 micrograms / day after 5 years. Its pregnancy rate is very low, with a cumulative pregnancy rate of 0.5 per 100 women years. Can be used effectively for 5 years. Women weighing more than 70 kg have a slightly higher pregnancy rate than women in general. Generally healthy women can choose Nopril because it is a simple progestin contraceptive, suitable for breastfeeding women and women who have contraindications to the use of estrogen and should not use compound oral contraceptives. The main side effect is menstrual disorders, with irregular bleeding at the beginning and amenorrhea at the later stage. In general, there is no need to remove it. However, if persistent irregular bleeding fails to treat, some women require removal. Occasionally, headache and weight gain are not necessary. The incidence of side effects due to subcutaneous implant bleeding is approximately. 70%, the duration is also long, so the patient should be patiently consulted before surgery. Because it is more common to continue with a small amount of bleeding, it will not cause anemia and infection. Increasing tolerance through consultation can reduce the termination rate.
- The Nopland II produced in Finland is a small rod made by mixing silica gel with L-methyl norethisterone, and a silicone film is applied to stabilize the release rate and prevent fracture. When two were placed at the same time, the release rate was about 45 g / day. After 3 years of use, the effects and side effects are similar to those of Noplete. China is gradually expanding clinical trials of this new method of contraception. Biodegradable subcutaneously buried plants under research in foreign countries include capronol and norethindrone particles.
- No matter what type of subcutaneous implant, once placed for long-term use, the contraceptive effect is good, and it has a positive role in promoting the harmony of couples' sexual life. If a small amount of irregular vaginal bleeding occurs for a long time after the skin is buried, the couple can still have sex.