What are the advantages and disadvantages of using gene therapy for HIV?

When using gene therapy for HIV there are several positive aspects, but also some fall. People are now considering this type of therapy even more because the success is still growing. Theoretically, the use of gene therapy for HIV is very effective and successful, but in a practical sense there is a long way to be considered an effective medicine. During this process, doctors must risk the destruction of internal body functions to enter new genes. The advantages are that if the treatment is successful, there will be no grades of HIV. The disadvantages are that if any of the steps does not work, there is a huge chance that the patient may end up with even more health problems than what he had in the first place.

HIV virus affects CD4 T cells in the body, which then produce other cells with the same disorder, which eventually destroys the entire immune system. The immune system of the body consists of various internal parts, such as the grind, lymph nodes, bone marrow, etc. In problems with bone marrow, the stem cell is damaged. If possibleThe gene that has been modified to stop HIV can be placed in a stem cell, then it can fill the body without reproducing the affected cells. The HIV virus simply dies because it has nothing to damage.

Studies involving gene therapy for HIV have verified several successful cases. Scientists have found that the bodies of people who were treated had no HIV signs after three years. Another technique used in gene therapy for HIV is based on the base of two individual co -ceptors, CCR5 and CXCR4 cells that destroy the virus. It is a positive aspect of gene therapy, due to alternatives that do not give the real healing of this deadly virus.

modified genes, as a medicine, are packed with a harmless virus called vector and inserted in the body during the process of gene therapy for HIV. The disadvantages of HIV gene therapy relate to the vector. Cases have shown that this may be a risk if the vector does not respond to administrationThe cells or vector itself can combine with another virus inside and cause even greater risk.

For the use of a vector for inserting a modified gene into a stem cell, it will be necessary to destroy the remaining immune system many times. Chemotherapy is used to obtain this result, because there is still a chance that the remaining immune system of the body will consider the vector to be an attacker and destroy it. As with any other type of aggressive medical procedure, there is always a possibility that something goes wrong, a negative aspect of using gene therapy for HIV.