What factors affect sufficient dose of cefazoline?

Many factors affect sufficient dose of cefazoline, especially what it is used for and the severity of the condition. Cefazoline is a injection antibiotic used to treat sensitive bacterial infections and surgical prophylaxis. In most countries, it is only available according to the regulation and dosing of cefazoline must be provided by a trained medical worker because it is injected. According to the manufacturer, this may be known under different trade names in different countries. It works by inhibiting the synthesis of cell walls of sensitive bacterial organisms and can be used to treat the urinary tract, airways and heart infection. The medicine physician can send a sample to the pathological laboratory such as urine, blood or tissue to determine the susceptibility to cephazoline organism causing infection. Doses can range from 500 mg to 1.5 g and can be administered twice, three or four times a day for up to 10 or more days. Regardless of the prescribed dose of cefazoline, it is necessary to complete the whole course to preventILO development of resistant organisms that can make the treatment of future bacterial infections more difficult.

Cefazoline pediatric dose is usually determined by weight and can range from 25 to 50 mg per kilogram, in some serious cases up to 100 mg per kilogram, divided into three or four doses per day. The severity of the infection will again determine sufficient dose and duration of treatment. In adults and children with kidney dysfunctine, the dose of cefazoline may need to be adjusted.

cefazoline can be used perioperatively for surgical prophylaxis or prevention of infection during surgery. The usual dose of cephazolin in this adult scenario is 1 g served half an hour to an hour before the operation. If the operation is long, additional smaller doses may be administered during the procedure to ensure the corresponding antimicrobial levels throughout. Usually continues the day after surgery, but in cases where infection is a significant riskcan be extended to several days.