What Factors Affect B12 Injection Dosage?
Vitamin B12 injection, mainly used for megaloblastic anemia, can also be used as an adjuvant treatment of neuritis.
- Drug Name
- Vitamin B12 injection
- Drug type
- Work Injury Medical Insurance Class A Double Span
- Hanyu Pinyin
- Wei Sheng Su B12 Zhu She Ye
- Use classification
- Vitamin B supplements
- Vitamin B12 injection, mainly used for megaloblastic anemia, can also be used as an adjuvant treatment of neuritis.
Vitamin B12 injection ingredients
- The main ingredient of this product is vitamin B 12 , chemical name: Co- [- (5,6-dimethylbenzimidazolyl)]-Co ammonium cyanocobalyl ammonium.
Chemical Structure:
Molecular formula: C 63 H 88 CoN 14 O 14 P
Molecular weight: 1355.38
The auxiliary material is: sodium chloride.
Properties of Vitamin B12 Injection
- This product is a pink to red clear liquid, odorless and tasteless.
Vitamin B12 injection indications
- It is mainly used for megaloblastic anemia and can also be used as an adjuvant treatment of neuritis.
Vitamin B12 injection specifications
- (1) 1ml: 0.25mg (2) 1ml: 0.5mg (3) 1ml: 1mg
Vitamin B12 injection dosage
- Intramuscular injection, adult, 0.025 0.1mg every day or 0.05 0.2mg every other day. When used for neuritis, the amount can be increased.
Vitamin B12 injection adverse reactions
- Intramuscular injection can cause rash, itching, diarrhea, and allergic asthma, but the incidence is low, and anaphylactic shock is rare.
Vitamin B12 injection contraindications
- still uncertain.
Vitamin B12 injection precautions
- 1. Can cause allergic reactions, and even anaphylactic shock, should not be abused.
2. When possible, the blood vitamin B 12 concentration should be monitored during the medication.
3 Hyperuricemia may occur in patients with gout when using this product.
4. For the treatment of giant cell anemia, blood potassium should be checked in the first 48 hours to prevent hypokalemia.
Vitamin B12 injection for pregnant and lactating women
- still uncertain.
Vitamin B12 injection for children
- Intramuscular injection 25 100g / time, once a day or every other day. Avoid repeated dosing at the same site, and be especially careful with newborns, premature babies, infants, and young children.
Vitamin B12 injection for the elderly
- still uncertain.
Vitamin B12 injection drug interactions
- Aminosalicylic acid can reduce the effect of this product.
Vitamin B12 injection overdose
- still uncertain.
Vitamin B12 injection pharmacology and toxicology
- This product is an anemia drug. Vitamin B 12 participates in methyl conversion and folic acid metabolism in the body, and promotes the conversion of 5-methyltetrahydrofolate to tetrahydrofolate. In the absence, it can cause DNA synthesis disorders and affect the maturation of red blood cells. This product also promotes the conversion of methylmalonic acid to succinic acid and participates in the tricarboxylic acid cycle. This effect is related to the synthesis of nerve myelin lipids and the maintenance of myelinated nerve fibers intact, and the nerve damage of vitamin B 12 deficiency may be related to this.
Pharmacokinetics of Vitamin B12 Injection
- After intramuscular injection, the absorption is rapid and complete, and the blood concentration reaches a peak in about 1 hour. It is widely distributed in the body, but it is mainly stored in the liver. The total adult storage is 4-5 mg; The more excreted.
Vitamin B12 injection storage
- Protected from light and sealed.
Vitamin B12 injection packaging
- 1 ml x 10 ampoules.
Vitamin B12 injection expiration date
- 36 months
Vitamin B12 injection standard
- "Chinese Pharmacopoeia" 2010 edition two
- [1]