What Factors Affect Estrace Dosage?

Estrogen is a substance that promotes the development of secondary sexual characteristics and the maturation of sexual organs in female animals. It is produced by the female animal's ovaries and placenta. The receptors for estrogen are distributed in the uterus, vagina, breast, pelvis, and skin, bladder, urethra, bones and brain. Therefore, estrogen has a wide range of important physiological functions, not only promoting and maintaining female reproductive organs and secondary sexual characteristics Physiological effects, and have significant effects on endocrine, cardiovascular, metabolic systems, bone growth and maturity, and skin. Natural estrogens are mainly estradiol, estrone, and estriol; most of the currently used estrogen drugs in clinical practice are synthetic derivatives based on estradiol, such as estradiol benzoate and estradiol valerate. Alcohol, ethinyl estradiol, ethinyl estradiol, estrone and so on.

Basic Information

Chinese name

Estrogen

Foreign name

estrogenic hormone

Species

Plant hormones, animal hormones

Physiological effect

Promote the appearance of secondary sexual characteristics

Types of

Female hormone

To source

Ovary, placenta

Estrogen indication

1. Perimenopausal syndrome: estrogen can be used for alternative treatment.

2. Breast pain and wetting: Large doses of estrogen can interfere with the action of prolactin, inhibit milk secretion, and relieve pain.

3. Ovarian insufficiency and amenorrhea: Replacement therapy with estrogen can promote the development of external genitalia, uterus and secondary sexual characteristics. Combined with progestin, it can produce artificial menstrual cycle.

4. Osteoporosis: Prevent and treat with small doses.

5. Functional uterine bleeding estrogen can promote endometrial hyperplasia, repair bleeding wounds and stop bleeding, and can also be appropriately combined with progestin to adjust the menstrual cycle.

6. Advanced breast cancer Patients with advanced breast cancer for more than five years after menopause are treated with estrogen, but patients before menopause are disabled.

Clinical application of estrogen

As directed by your doctor.

Estrogen adverse reaction

Large doses may have nausea and vomiting, breast tenderness, endometrial hyperplasia and uterine bleeding. Long-term high-dose application may increase the risk of breast cancer, estrogen alone may increase the risk of endometrial cancer, and may increase the risk of cardiovascular and cerebrovascular diseases and venous thrombosis.

Estrogen contraindications

Known or suspected pregnancy, unexplained vaginal bleeding or endometrial hyperplasia, breast cancer, sex hormone-related malignancies; 6 months of active venous or arterial thromboembolic disease Liver and kidney dysfunction, hematoporphyria, otosclerosis, and systemic lupus erythematosus are contraindicated.

Note: The above content is only for introduction, the drug use must be carried out by a regular hospital under the guidance of a doctor.