What factors affect estradiol dosing?
estradiol dosage is influenced by many different factors, the most important two are the condition that the drug is used for treatment and the application method. For most conditions, the oral dose of estradiol is not more than 2 milligrams (mg) per day. This is suitable for the treatment of problems after menopause, hypoestrogenism, oophorectomy and atrophic vaginitis. However, if the drug is given as a local cream, the dose is reduced to 0.025 mg to 0.1 mg per day. In other conditions such as osteoporosis, oral estradiol dose is only 0.5 mg per day.
Estradiol is an estrogen supplement that is used as treatment in various situations. The most common is prescribed a drug that helps control the symptoms associated with menopause. In addition, the drug can be used for other diseases such as osteoporosis, prostate cancer and breast cancer. Hypoestrogenism and atrophic vaginitis also benefit from estradiol. In general, the drug is given daily, and sometimes with a five -day break from treatment every month.
The most important factor that affects estradiol dosing is the condition used for treatment. For most conditions, the dose between 1 and 2 mg daily is administered orally. This is suitable for the treatment of hypoestrogenism, atrophic vaginitis and atrophic urethritis. For problems after menopause, the dose may start from 0.45 mg per day, but still has a maximum of 2 mg. The dose of estradiol for palliative breast cancer is much more, at 10 mg served three times a day.
Another key factor in determining the correct dose of estradiol is the drug application method. Most often the drug is used in the form of tablets, but is also available as a local patch and vaginal cream. The local patch is applied to the affected area and its dose is usually lower in no need for a lower dose. For example, if the drug is used to treat primary ovarian failure, an oral dose is between 1 and 2 mg per day, while the local patch dose is 0.025 to 0.1 mg per day.
patch are applicationsWoods on the patient's body on the hairless part of the skin other than the breasts. In general, different positions must be used in rotation, so no space is used more than once a week. Repair is usually used one to twice a week.