What Is an Amphetamine Overdose?

Amphetamine is a non-catecholamine-like sympathomimetic drug, which excites adrenergic nerve endings and the central nervous system, raises hypertension, constricts peripheral blood vessels, excites the heart, relaxes bronchial and intestinal smooth muscles, dilated pupils, and contracts bladder sphincter. This product is quickly absorbed from the intestine, and can be completely absorbed after 1-2 hours. About 30-40% of the product is destroyed by deamination in the liver, and the rest is excreted from the kidney in the original form. The poisoning dose of this product is 15-20mg once. Those who are sensitive to this product only have 2mg of poisoning symptoms. The minimum lethal dose is approximately 250 mg.

Amphetamine poisoning

1. The main clinical manifestations are central nervous system excitement, patients with emotional instability, agitation, fantasy, anxiety and

Diagnose based on

1. Overdose

Principles of Amphetamine Poisoning Treatment

1. Promote the excretion of poisons.

2. Fight the excitatory effect of the central nervous system of this product.

3. Prevention and treatment of respiratory and cardiac arrest.

4. Symptomatic supportive treatment.

Principles of medication for amphetamine poisoning

1. To promote the excretion of poisons, oral or nasal ammonium chloride, or intravenous infusion of vitamin C.

2. To counter the central nervous system excitatory effect of this product, haloperidol can be used.

3. Hemodialysis therapy if necessary.