What Is Lornoxicam?
Lornoxicam is a chloride of tenoxicam. Its effects are similar to piroxicam, with analgesic, anti-inflammatory and antipyretic effects. It can selectively inhibit COX-2, and its intensity is slightly weaker than that of piroxicam. Activate the opioid neuropeptide system and exert a central analgesic effect. The antipyretic effect of this product is weak, the required dose is 10 times the anti-inflammatory dose. Oral absorption is slow, reaching peak drug concentration in 24 hours. Food may reduce its absorption rate by 20% and delay its absorption rate. Distributed throughout the body and also in the synovial fluid.
- Drug Name
- Lornoxicam
- Alias
- Corkscrew
- Dosage form
- injection,
Basic Information
- Can be used for acute pain, acute sciatica or low back pain after obstetrics and gynecology and orthopedic surgery. Can also be used for chronic low back pain, arthritis, rheumatoid arthritis and ankylosing spondylitis.
- 1. intramuscular injection (> 5 seconds) or intravenous injection (> 15 seconds)
- 8 mg / time, 2 times / day, the maximum amount does not exceed 24 mg / day. Oral dosage form, 8 to 16 mg daily in pain, divided into 2 to 3 times, the maximum daily dose of 16 mg.
- 1. Gastrointestinal adverse reactions are about 16%, general adverse reactions and / or central nervous system disorders 5%, skin reactions 2%.
- 2. Common abdominal pain, diarrhea, dizziness, headache, as well as elevated serum urea nitrogen and creatinine, abnormal liver function.
- 3. Occasional insomnia, drowsiness, hair loss, rash, edema, increased or decreased blood pressure, palpitations, liver dysfunction, and tinnitus.
- Medication should be stopped when gastrointestinal bleeding occurs. Patients with gastrointestinal diseases must pay special attention when using this product for the first time. Long-term use of this product must be regularly checked for blood and liver and kidney function.
- Acute gastrointestinal bleeding or active ulcers, moderate to severe renal impairment, severe liver impairment, severe heart dysfunction, and pregnant and lactating women are contraindicated. Disabled under 18 years.
- Use with caution in the elderly, asthma, people with impaired liver and kidney function, and those with a history of gastrointestinal bleeding or duodenal ulcer, and those with coagulopathy.
- Note: The above content is only for introduction, the drug use must be carried out by a regular hospital under the guidance of a doctor.