What Is Naproxen Gel?

Naproxen capsules are used to treat rheumatoid and rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout, arthritis, and tenosynovitis. It can also be used to relieve pain caused by sprains, contusions, injuries and dysmenorrhea. ^[1] .

Drug Name: Naproxen capsules
Hanyu Pinyin: Nai Pu Sheng Jiao Nang

Drug type: Occupational injury medical insurance
Use classification: Carboxylic acids

Naproxen capsule ingredients

Naproxen

Naproxen capsule indications

For the treatment of rheumatoid and rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout, arthritis, tenosynovitis. It can also be used to relieve pain caused by sprains, contusions, injuries and dysmenorrhea.

Naproxen Capsule Specifications

(1) 0.125g
(2) 0.2g
(3) 0.25g

Naproxen capsules dosage

oral
1. Usual Adult:
(1) Resistant to rheumatism, 0.25 to 0.5 g each time, once in the morning and evening, or 0.25 g in the morning and 0.5 g in the evening;
(2) Pain relief, 0.5g for the first time, 0.25g if necessary later, and every 6 to 8 hours if necessary;
(3) Acute onset of gouty arthritis, 0.75g for the first time, 0.25g for the next time, every 8 hours, until the acute attack ceases;
(4) Dysmenorrhea, 0.5g for the first time and 0.25g if necessary, every 6 to 8 hours.
2. Commonly used in children: anti-rheumatic, 5mg / kg once per body weight, twice a day.

Naproxen capsules adverse reactions

1. Itchy skin, shortness of breath, dyspnea, asthma, tinnitus, lower limb edema, burning sensation, indigestion, stomach pain or discomfort, constipation, dizziness, drowsiness, headache, nausea and vomiting.
2. Blurred vision or vision impairment, hearing loss, diarrhea, oral irritation or pain, palpitation, and sweating.
3 Gastrointestinal bleeding, kidney damage (allergic nephritis, nephropathy, renal papillary necrosis and renal failure, etc.), urticaria, allergic rash, mental depression, muscle weakness, hemorrhage or granulocytopenia, and liver function damage are rare.

Naproxen capsules contraindications

Allergic history of this product or similar drugs, asthma, rhinitis and nasal polyp syndrome caused by aspirin or other non-steroidal anti-inflammatory drugs should be disabled; patients with active gastric and duodenal ulcers are prohibited.

Naproxen capsules precautions

1. Cross-allergies. People who are allergic to aspirin or other non-steroidal anti-inflammatory drugs are also allergic to this product.
2. Interference to diagnosis: can affect the determination of 5-hydroxyindole acetate (5-HIAA) and 17-ketosteroids in urine.
3 The following conditions should be used with caution: when there is a coagulation mechanism or platelet dysfunction, asthma, cardiac insufficiency or hypertension, liver and kidney dysfunction.
4 For long-term medication, liver, kidney function, blood, and eye examinations should be performed regularly. The dose must be adjusted according to the patient's response to the drug. Generally, the lowest effective amount is used.

Naproxen capsules for pregnant and lactating women

1. The research on the effects of this product on the fetus is not enough. Because other non-steroidal anti-inflammatory drugs can cause the fetal arterial duct to close prematurely, and it can inhibit the prostaglandin synthesis and cause dystocia or prolonged labor, so pregnant women should not be used unless otherwise .
2. The concentration of this product secreted into milk is equivalent to 1% of the blood concentration, it is not suitable for lactating women.

Naproxen capsules for elderly

Use with caution.

Naproxen capsules overdose

Urgent treatment should be given for excessive poisoning, including vomiting or gastric lavage, oral activated carbon and antacids, symptomatic and supportive therapies, and rational use of diuretics.

Pharmacological effects of naproxen capsules

This product is a non-steroidal anti-inflammatory drug. Its analgesic, anti-inflammatory, and antipyretic effects work by inhibiting prostaglandin synthesis.

Pharmacokinetics of naproxen capsules

The absorption is rapid and complete after oral administration, and the plasma concentration reaches a peak 2 to 4 hours after oral administration. The absorption rate decreases when taken with food, magnesium and aluminum-containing substances, and accelerates absorption when taken with sodium bicarbonate. The plasma protein binding rate is higher than 99%. t _{1/2 is} typically 13 hours. Metabolized in the liver, excreted by the kidneys. About 95% are excreted in the urine in their original form and their combinations.