What is the resistance to neomycin?
Neomycin resistance is a decrease in sensitivity to antibiotic neomycin. This drug can be used in the treatment and prevention of some types of infections. It is also used in medical research, where selective use of neomycin resistance can be used to indicate cellular cultures. The study of how and why bacteria develop resistance to this and other antibiotics is important for medical care providers and researchers. They have specialized independent molecules deoxyribonucleic acid (DNA) known as plasmids that can be reproduced independently by the DNA organism. When the bacteria is replicated, it can pass the plasmids the next generation, but the organisms can also replace them with each other. When DNA bears a drug resistance gene, it can rapidly spread the bacterial population through the horizontal gene transmission.Tial or full resistance. Over time, this can lead to a fully resistant strain that will not respond to the antibiotic. Neomycin resistance usually involves organisms that colonize the skinand intestines.
In the practice of medicine, resistance to antibiotics can be an important problem. If a patient with resistant infection receives an incorrect antibiotic, the drug does not kill bacteria, which will potentially allow infection to get much deteriorated. Some organisms can bear resistance genes for multiple drugs, which can complicate medical treatment. For this reason, antibiotics are used with care in medical practice, especially in the case of neomycin, which can also damage the liver and kidneys and therefore the drug is not the first choice.
Scientists can use plasmids carrying resistance to neomycin to their advantage. When working with cells in culture, they connect the plasmiddo genes they study. Their aim is to put the gene into cells in a process called transfection. Cells can be grown to allow them to start expressing the gene and then treated with neomycin. Cells that have not been transfected, die while others survive and create clean and hundreda plug -in cell line.
In some scientific laboratories, it may be more effective to order a scientific bid company, in which case the supplier develops DNA for transfection and sends it to the laboratory. Others can handle their own processing, which allows scientists to customize genes and markers for specific studies. Neolycin resistance is one of many tools that can be used to indicate a cell line for research purposes.