What Is the Connection Between Aspirin and Cholesterol?

Compound aspirin tablets are indicated for fever, headache, neuralgia, toothache, menstrual pain, muscle pain, and joint pain.

Compound aspirin tablets are indicated for fever, headache, neuralgia, toothache, menstrual pain, muscle pain, and joint pain.

Drug Name

Compound aspirin tablets

Drug type

Prescription drugs, medicines for medical workers' injuries

Special medicine

Psychotropic drugs

Compound aspirin warnings

Please read the instructions carefully and use under the guidance of a physician. It is strictly prohibited for food and feed processing.

Compound Aspirin Tablets Ingredients

This product is a compound preparation, and its components are: each tablet contains aspirin 0.22g; finacetin 0.15g; caffeine 35mg.

Compound aspirin tablets

This product is a white tablet.

Indications of Compound Aspirin Tablets

For fever, headache, neuralgia, toothache, menstrual pain, muscle pain, joint pain.

Compound aspirin tablets specifications

Compound preparation: each tablet contains 0.22g of aspirin; 0.15g of fenacetin; 35mg of caffeine.

Compound Aspirin Tablets Usage and Dosage

Oral, adult: 1-2 tablets at a time, 3 times a day after meals.

Adverse effects of compound aspirin tablets

This product is a compound tablet consisting of aspirin and phenacetin. Aspirin's more common adverse reactions are gastrointestinal reactions such as nausea, vomiting, upper abdominal discomfort or pain, which can disappear after stopping medication; gastrointestinal bleeding or ulcers can occur during long-term or large-scale application, which can appear after taking a certain course of treatment Reversible tinnitus and hearing loss; a small number of patients can develop allergic reactions such as asthma, urticaria, angioedema or shock, which can cause death; severe doses can cause liver and kidney function damage. Finacetin can cause renal papillary necrosis, interstitial nephritis, and acute renal failure, and may even induce renal pelvic cancer and bladder cancer. Finacetin also easily causes hemoglobin to form methemoglobin, reduces the oxygen-carrying ability of the blood, and causes cyanosis. In addition, phenacetin can cause hemolysis and hemolytic anemia, and it is toxic to the retina. Long-term use of phenacetin can also cause dependence on drugs. Finacetin can also cause liver damage.

Compound aspirin tablets contraindications

Those who are allergic to aspirin or other non-steroidal anti-inflammatory drugs and caffeine, and those with hemophilia, active peptic ulcer and other causes of gastrointestinal bleeding are contraindicated. Infants under 3 months of age are disabled.

Precautions for compound aspirin tablets

Use with caution for children under the age of 6 and elderly and infirm.
2. People with asthma and other allergic reactions, those with glucose-6-phosphate dehydrogenase deficiency, those with gout, those with heart, liver, and kidney dysfunction, those with thrombocytopenia, and those with bleeding tendency should be used with caution.
3. For long-term large-scale application, the hematocrit, liver function and serum salicylic acid content should be regularly checked.
4. Cross-allergic reaction: When you are allergic to this product, you may be allergic to another salicylic acid or another non-salicylic non-steroidal anti-inflammatory drug. You must be alert to the possibility of cross-allergy.
5. Interference to diagnosis: When the daily dosage of aspirin exceeds 2, 4g, false positive results may occur in the copper sulfate urine glucose test and false positive results in the glucose enzyme urine glucose test, which may interfere with the urine ketone test; when the blood concentration exceeds 130 g / At ml, falsely high values can be obtained by colorimetric determination of blood uric acid, but it is not affected by the urase method; urinary 5-oxindoleacetic acid (5-HIAA) can be interfered by aspirin when measured by urine; urine The determination of vanillyl mandelic acid (VMA) can be high or low due to different methods. Aspirin inhibits platelet aggregation and can prolong bleeding time. Hepatic function tests, when the blood concentration is> 250 g / ml, alanine amino Transferase, aspartate aminotransferase, and serum alkaline phosphatase can be abnormally changed, and return to normal when the dose is reduced. Large-dose applications, especially when the blood concentration is> 300 g / ml, prothrombin time can be extended; daily When the dosage exceeds 5g, the serum cholesterol can be reduced. As aspirin acts on the renal tubules, potassium excretion increases, which can lead to a decrease in blood potassium. When applying this product in large doses, the serum thyroid gland is measured by radioimmunoassay (T4) and tri-iodo-thyronine (T3) available low result; as aspirin and phenol red excretion competitive tubules, decreased excretion of the phenolsulfonphthalein (PSP i.e. excretion test).

Compound aspirin tablets for pregnant and lactating women

Aspirin in this product is easy to pass through the placenta. Considering the possible effects on the fetus, it is not suitable for pregnant women. After taking this product, lactating women can reach a certain concentration of aspirin in breast milk, so it may cause adverse reactions such as bleeding tendency of infants when long-term high-dose application.

Compound aspirin tablets for children

Child patients, especially those with fever and dehydration, are prone to toxic reactions. Acute febrile diseases, especially children with influenza and chickenpox, may develop Rey Syndrome. Children under 6 years should be used with caution, infants under 3 months of age are prohibited.

Compound aspirin tablets for elderly

Elderly patients are susceptible to toxic reactions when taking this product due to decreased renal function, and should be used with caution or appropriate reductions.

Compound aspirin tablets drug interactions

still uncertain.

Compound aspirin tablets overdose

Overdose of this product should be avoided. Overdose can cause damage to the central nervous system, liver and kidney function, blood system, etc., and should seek medical attention if it occurs.

Pharmacology and Toxicology of Compound Aspirin Tablets

This product is a compound antipyretic and analgesic. Among them, aspirin and phenacetin have antipyretic and analgesic effects, can inhibit the synthesis and release of prostaglandins in the hypothalamus, restore the normal response of temperature-sensing central sensory neurons, and have antipyretic and analgesic effects. The synthesis of prostaglandins, etc. plays analgesic, anti-inflammatory and anti-rheumatic effects, and aspirin also inhibits platelet aggregation. Caffeine stimulates the cerebral cortex, increases the sensitivity to the outside world, and constricts the cerebral blood vessels, strengthening the effects of the first two drugs to relieve headache.
Acute toxicity test results: The oral LD50 of rats was 1500mg / kg; the oral LD50 of mice was 1100mg / kg.

Pharmacokinetics of Compound Aspirin Tablets

still uncertain.

Compound aspirin tablets storage

Protected from light and sealed.

Compound Aspirin Tablets Packaging

Plastic bottle packaging: 100 tablets / bottle; 1000 tablets / bottle; plastic film packaging: 400 tablets / box; aluminum-plastic blister packaging: 12 tablets / board; 15 tablets / board.

Validity of Compound Aspirin Tablets

24 months.

Compound Aspirin Tablets

Ministry of Health Drug Standard WS1 -65 (B) -89. ^[1]