What Is the Treatment for Thyroid Calcification?

Calcification is one of the most common imaging signs of thyroid lesions, accounting for 15.7% to 38.7% of benign lesions and 49.6% to 78.8% of malignant lesions.

Calcification is one of the most common imaging signs of thyroid lesions, accounting for 15.7% to 38.7% of benign lesions and 49.6% to 78.8% of malignant lesions.
Western Medicine Name
Thyroid calcification
Disease site
Thyroid nodules
The main symptoms
Single or multiple thyroid bodies are found, with acute onset, fever, sore throat, clear nodule and surrounding thyroid tissue, slow onset and development, no obvious conscious symptoms in the early stage, etc.
Main cause
Calcium deposition
Contagious
Non-contagious
Types of
Coarse calcification

Causes of thyroid calcification and common diseases

The mechanism of calcification is still controversial. In the past, it was thought that due to the thickening of the basal layer of the papillary structure, secondary intravascular thrombosis, calcification, and tumor cell necrosis, or due to factors such as necrosis and calcification of tumor emboli in the lymphatic vessels, which appeared on ultrasound examination. Coarse calcification or peripheral calcification. However, these theories cannot explain how calcification is formed in non-papillary tumors (such as meningioma), nor can it explain the cause of cytoplasmic granulosomes. Therefore, other theories suggest that interstitial vitreous degeneration followed by calcification, or similar to the formation of grit bodies by nanobacteria in serous tumors.

Differential diagnosis of thyroid calcification

Thyroid calcification is an important indicator for the diagnosis of thyroid disease. When thyroid nodule calcification occurs, it can cause both thyroid malignancy and benign thyroid disease. However, compared with benign disease, malignant tumor is more likely to have calcification. Due to the rapid proliferation of cancer cells, the proliferation of blood vessels and fibrous tissue in tumors is prone to calcium deposition caused by nodule calcification. In addition, the tumor itself also secretes some substances such as glycoproteins, mucopolysaccharides, etc. to cause nodular calcification. Therefore, the possibility of calcification of thyroid cancer nodules is very high.

Thyroid calcification test

According to histological characteristics, calcification in thyroid lesions is divided into grit, interstitial calcification and ossification. Granular body is the most concerned type of calcification, and it is found in nearly 50% of papillary carcinomas. It is rare in other types of thyroid cancer, and it is extremely rare in benign thyroid lesions. Grit is a layered structure of concentric circles with a diameter of 50 to 70 m. It looks like loose sand and has an onion-like cut surface. It is often associated with tumor cells. It is common in the nipple fiber axis, fibrous interstitial, and solid. Tumor cells between nests.
Interstitial calcification has various forms, which can be expressed as regular or irregular granules, clumps, rings, arcs, or lines. Ossification is formed on the basis of interstitial calcifications. The two cannot be distinguished on the image. Its histological composition is similar to normal bone. Circular calcification is a typical manifestation of interstitial calcification.

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