What should I know about statins and grapefruit?
If you are taking medication for statin to reduce cholesterol, it is good to avoid grapefruit and grapefruit products. Statins and grapefruit do not mix because the components in grapefruit disrupt the way the statins decompose in the body. If the body cannot properly metabolize drugs reducing cholesterol, the drugs may accumulate in the patient system, resulting in overdose. The side effects of interaction between statins and grapefruit include potentially fatal damage to the liver, kidney and muscles. It is understandable that those who take statin drugs may want to add fresh grapefruit or grapefruit juice to their diet. Unfortunately, the grapefruit compound known as Bergamottin interferes into the enzymes needed to metabolize some statin drugs, including atorvastatin (Lipitor®), Simvastatin (Zocor®) and Lovastatin (Mevacor®). Evidence shows that only one case of grsp -consumption of apes of apes or grapefruit may be enough to make these medicines in your systemThey were, and the timing doesn't even matter much. Even if you eat or drink grapefruit products many hours after using pills, the risk is still present.
Statins and grapefruit are not the only significant interaction with drugs/fruit you must be aware of. Pomelos and Seville oranges may have a similar effect. Seville oranges are often included in fruit compote and marmalades and pomelos or Chinese grapefruit, citrus fruit from Southeast Asia, which can be found in ethnic markets. The problem of accumulation of a toxic drug similar to the one caused by the interaction of statins and grapefruit may occur when people mix other drugs with fruit containing bergamottin. These drugs include some antidepressants; calcium channel blockers; And hearts, HIV and anti-seizures.
Frozenly people who use statin medicines may not have to stay forever grapefruit or its juices. Seems to beThe metabolism of some cholesterol drugs, such as Pravastatin (Pravachol®), Fluvastatin (Lescol®) and Pitavastatin (Livalo®), is not affected in the same way as other statin drugs. However, some medical experts still recommend caution when combining two and suggest that patients delay grapefruit several hours after taking medication. If you like to eat grapefruit, be sure to talk to your doctor or pharmacist about possible interactions with your medicines. It may be possible to switch to an alternative medicine or reduce dosage so that you do not have to worry about the interaction between statins and grapefruit.