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Uric acidity (pH) is one of the contents of routine urine tests and reflects the kidney's ability to regulate the acid-base balance of body fluids. The body can excrete a large amount of acidic and alkaline substances through the urine to maintain the acid-base balance. Normal fresh urine is weakly acidic, with a pH between 4.5 and 7.9. The kidney needs to excrete about 50 to 100 mmol of fixed acid produced daily by food decomposition. Therefore, a high-protein diet can produce acidic urine, while eating foods containing less Urine is slightly alkaline in vegetables.

Basic Information

Chinese name
Urine pH
Symbol
pH
Reference
5 7
Definition
PH value of urine during routine urine test

Urine pH specimen collection

On an empty stomach, 10 ml of fresh morning urine was collected and submitted for inspection.

Clinical significance of uric acid

Physical decline
The diet is mainly animal-based and the pH value is lowered; during sleep at night, there is a slight respiratory acidosis, so the urine pH value decreases. Vigorous physiological activities, such as violent exercise, stress, hunger, and decreased urine pH during sweating.
2. Physiological increase
Plant-based, pH> 6. After a meal, gastric acid secretion increases, urine acid secretion decreases, and pH increases.
3. Pathological decrease
Decreased urine pH is seen in: respiratory or metabolic acidosis, diabetic ketoacidosis, gout, fever, hunger, emphysema, urate or cystine stones, urinary tuberculosis, nephritis, potassium-deficient metabolism Alkalosis, severe diarrhea. In addition, taking medications such as calcium chloride, ammonium chloride, potassium chloride, etc., lowers the urine pH.
4. Pathological increase
Increased urine pH is seen in: respiratory or metabolic alkalosis, bacterial decomposition of urea, renal tubular acidosis, gastric aspiration, long-term vomiting, infectious cystitis, and pyelonephritis. Proteus urinary tract infection showed alkaline urine.

Reference range of uric acid normal value

Normal people's urine is weakly acidic under ordinary dietary conditions, with a pH of about 6.5 and a fluctuation range of 4.5 to 8.0.

Cautions on uric acid

1. During the measurement, the urine time of the reagent tape is too long, and the urine pH decreases.
2. The urine specimen must be fresh, otherwise the bacteria may decompose the urine components and cause the pH to change, or the carbon dioxide generated by the decomposition of bicarbonate in the urine will naturally diffuse into the air and increase the pH.

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