What Is Squamous Tissue?

Atypical squamous epithelial cells refer to abnormal squamous epithelial cells whose morphological characteristics and pathological characteristics are not certain. This type of patients should be reviewed. Take care to avoid sexual life and vaginal medication before review. The presence of malignant lesions can be determined in conjunction with further cervical biopsy.

Squamous cells are based on the anatomical and histological structure of the cervix. The external vagina of the cervix is composed of squamous cells, and the inner mouth is composed of endometrial cells and metaplastic squamous cells. Under normal circumstances, the cells that can be obtained are basically mature squamous cells. There are two types of mature squamous cells: pre-keratinocytes and incomplete keratinocytes. Polygonal cells with blue or green cytoplasm in the Pap stain are pre-keratinocytes, while dark eosinophils with cytoplasm are incomplete keratinocytes. In the past, cervical cancer was thought to originate from basal cells of cervical squamous epithelium, but now this understanding is being challenged. Studies have found that it is impossible to reverse the mature stage of epithelial cells to the immature stage. In fact, 90% of cervical cancers originate from the transition zone and cervical canal, and there are no squamous underlying cells in these areas. Therefore, it is believed that cervical cancer of the cervix and vagina originates from underlying cells; cervical squamous cell carcinoma prepared cells are derived; cervical adenocarcinoma also originates from reserve cells ^[1]

Because it is a precancerous lesion, it must be closely observed.

If the biopsy is mild

Microscopic characteristics of squamous epithelial cells in various layers of normal cervix:

Surface layer cells: 40 60m cytoplasmic red stain is polygonal, nucleus is less than 5 7m, chromatin concentration is condensed. The nuclear-plasma ratio was 1:10. Middle layer cells: 30-60m cytoplasm is light blue or pink with polygonal shape, the nucleus is 10-12m larger than surface cells, and the chromatin is loose. The nuclear-plasma ratio was 2:10. Basal cells: 15-20 m round, oval and boat-shaped; cytoplasmic blue staining, nuclei 8-13 m. The nuclear-plasma ratio was 5:10. Basal cells: 8-10 m mostly round, rarely oval; cytoplasm is less dark blue, with nuclei 7-9 m. Basal cells are rarely found in cervical smears, and are only seen when the cervix has severe trauma. The nuclear-plasma ratio was 8:10 ^[2] .