What is a one -time RNA?
There are three basic macromolecules in all kinds of life. Ribonucleic acid (RNA) is one of these three and RNA has an amazing ability as the only stuck molecule to assume three -dimensional shapes by multiple hydrogen binding, which forms its secondary structural scaffolding. Other two necessary macromolecules are deoxyribonucleic acid (DNA) and proteins; Of these two, RNA has many similarities to proteins in the function and similarity to DNA in the chemical structure. There are also double RNA, but they are rare. The disposable RNA catalyzes biological reactions, is a receiver and a transmitter for cell signals and helps to control gene expression.
Since 2011, a one -time RNA has been the subject of seven Nobel Prizes. Many research between prices has made the discoveries of RNA duties, which has led to significant progress in the biological state of the Alekovic science. A disposable RNA was found in 1868, but still poorly Charawhich she received, and only in 1959 received the concentration of Nobel, when Ocho and Kornberg received the Nobel Prize in Medicine after the synthesization of RNA in the laboratory using the enzyme - again poorly characterized; It was not a real synthesis, but a degradation procedure. In the 1960s and 1970s, they were discovering that one -center RNA could not only carry genetic information, but also function as a catalyst for biological reactions and to discover that this type of replication of two -way streets could not only bear not only to carry not only genetic information but also function as a catalyst of biological reactions. In the 80s until 2006, four more prizes were awarded for discoveries in RNA haircut, more catalyzing functions, micro -function and RNA transcriptions.
Single -cut RNA is helpful in protein synthesis; When the proteins are formed in ribosomes, it is the assembly and assembly and assembly of the Andes together with the transmission RNA (TRNA) provides accompanying amino acids to join and form proteins. Ribosomal protein factories enoughThey do genetic information from MRNA and 80 thorn nucleotides are instrumental in amino acid translation into newly formed proteins. Using DNA as an enzyme, known as RNA polymerase, rewrites RNA for new springs of single -strand RNA. The same enzyme uses RNA Templates when RNA viruses, such as Poliovirus, try to replicate its viral material. There is a method of measurement and screening for a single -strand function of RNA important for understanding the bond between RNA and proteins. Nucleotide analog interference mapping (Naim) discovers the identity of specific RNA molecules that bind to proteins less well than RNA type bonds to better understand the mediation of protein.
AS RNA carries genetic information, RNA viruses contain RNA replication in their genomusna as a number of proteins coded by this genome. Some proteins protect this viral genome because it translates into a new cell host. These viruses with resident replication RNA in turn reverse rewriting DThey create a new single -strand RNA, which further spreads viruses. There are four groups of RNA viruses that spread measles, mumps, rabies, flu, yellow fever and horse encephalitis, and each group has its own method of replication of the genome of the virus.
It is known that rhinos, including conventional colds, are a one -time RNA, which is replicated in the cytoplasm cell by processing viral protease, which results in the release of proteins infected by the virus. The disposable RNA is also associated with the type of inflammation, which may be responsible for the heart fibrosis, which can lead to a block of heart in the fashion of autoimmune reaction, leading to congenital heart defects. However, there are discoveries that can use the genes of genes in the body that could cause the disease. Knowing that there are small parts of RNA that disrupt the production of proteins, some believe that one day a one -off RNA will supply pharmacies directly to proteins.