What is the connection between calcitonin and PTH?

There are a number of connections between calcitonin and hormone of body semi -bodies (PTH). Both substances are both proteins that serve as hormones and cause changes in the body binding to cellular receptors. Both are made in similar areas of the body. In addition, both hormones play an important role in maintaining the right calcium and phosphate in the blood. Calitonin and PTH are also regulated by their own blood levels and also blood calcium concentration. Calitonine is produced by paraphollicular cells, also known as C-cells, thyroid. The endocrine organ located in the front neck area, the main function of the thyroid gland is to produce thyroid hormone, the substance important in regulating the body metabolism. There are four glands called the body gland -shymmetrically in the rear aspect of the thyroid gland. Their main function is to produce PTH, which is made by the main cells of these glands. Both of these substances are polypeptides, which means they are composed of amino acids connected together in a specific order. These substances ZpThey cause changes in the body's operation by binding to cellular receptors.

Calitonin and PTH are further connected because both help regulate calcium and phosphate levels throughout the body. In general, the effect of PTH is to increase calcium and phosphate levels in the blood; This makes it an increase in the release of these minerals from the bone and creates an activated form of vitamin D, which helps the intestines absorb more calcium and increase the reabsorption of calcium in the kidneys. Calitonine has the opposite effect because it lowers calcium levels in the blood. Overall, PTH has a strong effect on the concentration of calcium in the blood, while calcitonin has a milder effect and is not critical in the help of the body to maintain normal calcium levels in the blood.

similarities in calcitonin and PTH also exist in how the production of these hormones is regulated. Low calcium levels in the blood stimulate the production of PTH, while high levels increase calcitonin secretion. Both hormones are also regulated by negativeIt means that with high blood levels of these hormones it will turn off further production. For example, the main cells of the body can feel when they are high in PTH in the blood, and when detecting this condition, they end PTH production.