What is the stratum granulosum?
stratum granulosum, sometimes known as a granular layer, is one of the layers in the epidermis or outer part of the skin. There are five layers in the epidermis and the stratum granulosum is in the middle. There are two layers under the stratum granulosum, with the lowest consisting of actively dividing cells, while the above are two layers of flattened inactive cells with the upper, the outer layer constantly shed. Stratum granulosum creates a waterproof barrier between these outer layers and inner living cells. In medicine, a study of skin and conditions that affect it is called dermatology. Cells in the epidermis are known as keratinocytes because they create a type of protein called keratin, which is used to strengthen the skin. In the epidermis, the lowest or basal, the layer constantly produces new cells, with older cells moving up to form a layer layer layer or layer. In the cells of the layer, they are more flattering and full of keratin. Older cells in the layer are replaced again and move up to form a granThe lining layer, where they begin to lose the cores and at a time when they moved up with two more layers to reach the peak of the epidermis, became flattened dead scales.
Since stratum granulosum is impermeable for water soluble substances and water, it forms a barrier between active cells of the lower epidermis and external dead cells. It is believed that granular cells contain special lamellar granules that eliminate oily leaves. These are stored in the spaces between the cells of the stratum granulosum and consists of a kind of waterproof sealant that creates a barrier protecting the bottom layers of skids.
stratum granulosum is about three to five cells; Along with lamellar granules, these cells also contain what is called keratohyalin granules. In people who have a disease known as ichthyosis vulgaris, where skin and scaly skin have been found that the keratohyalin granules are reduced to the beginninghere or missing. The protein called Filaggin is produced by the cells of the granular layer and is usually the main substance found inside the keratohyalin granules. It is believed that Filaggin plays an important role in the structure of the outer layer of the skin and also helps it maintain moisture. Ichthyosis vulgaris can be treated with hydration of the skin and adding ointment at the top to stop the leakage of moisture.