What Is Clinical Pharmacology?

Clinical pharmacology is a discipline that studies the interaction between drugs and the human body. It is based on pharmacology and clinical medicine. The nature and mechanism of side effects and the law of drug interactions, etc .; The purpose is to promote the combination of medicine, basic and clinical, guide the rational use of medicine, improve the level of clinical treatment, and promote the development of medicine and pharmacology.

Clinical pharmacology

(Subject name)

Clinical pharmacology is a discipline that studies the interaction between drugs and the human body. It is based on pharmacology and clinical medicine.

Clinical Pharmacology and

The brief history uses human body as an experiment, although it can be traced back to a very early time. For example, in our feudal society, there is a record of "Jun You Sick, Drink Medicine, and Try It First". Direct pharmacology for foreign employment

Clinical Pharmacology Research

In modern times, China's work in these two fields has been actively carried out. Because the object of study is human, one should be cautious.

Clinical Pharmacology and

(I) Responsible for clinical pharmacological research of new drugs

The clinical pharmacology base of the Ministry of Health should actively undertake the clinical pharmacological research of a drug, and it is technically responsible to guide and assist clinical hospitals in various regions to conduct and do clinical trials and validation of new drugs. And is responsible for formulating clinical research plans, organizing clinical trials, and jointly with the provinces, autonomous regions, municipalities, and designated hospitals to complete the clinical research tasks of new drugs approved by the Ministry of Health or provincial, autonomous regions, and municipalities. After the clinical study is completed, a scientific summary report is written and sent to the development unit and copied to the Ministry of Health and the relevant provincial, autonomous region, and municipal health departments and bureaus.

(2) Clinical re-evaluation of produced drugs

Each clinical pharmacological base should actively carry out the re-evaluation of the listed drugs for certain types of drugs undertaken, and carry out social surveys and collections of drugs with uncertain effects, adverse reactions, or other reasons that endanger people's health according to the plan of the Ministry of Health and the actual situation of the unit to collect Data, combined with experimental research, analysis and adjustment, and draw scientific conclusions. Submit evaluation opinions to the Ministry of Health, the Department of Health and the Bureau.

(3) Responsible for drafting clinical trial indicators and evaluation principles for various drugs

Each clinical pharmacology base is responsible for drafting the requirements, content and observation indicators, clinical evaluation principles, and clinical evaluation principles of various drugs for clinical trials and clinical verification, so that the clinical research of various drugs meets standardized requirements.

(4) To guide the rational use of drugs in clinical monitoring of adverse drug reactions and improve the level of drug treatment.

When conducting clinical pharmacology research, each clinical base should accumulate experience in the safe and effective use of new and old drugs, conduct scientific summary at any time, carry out tasks such as epidemiological studies of adverse drug reactions and investigation of drug abuse, and have the responsibility to guide doctors Reasonable medication.

(5) Training on clinical pharmacology expertise for doctors conducting clinical research on new drugs

Beijing Medical University, Shanghai Medical University, Zhongshan Medical College of Sun Yat-sen University (formerly Sun Yat-Sen Medical University), three clinical training doctors at the clinical bases of the Ministry of Health, and doctors from provinces, autonomous regions, and municipalities designated to conduct clinical trials of new drugs at least annually A training course can also be organized as a small training course. Other clinical pharmacological bases can also gradually create conditions and run training courses for local clinical pharmacological backbones. The bases can communicate horizontally and communicate with each other, and gradually write a unified national clinical pharmacology handout, so as to continuously improve the level of training and work for the construction of a clinical pharmacology team in China.

(6) Carry out professional consultation on pharmacology and exchange of information and information

All clinical pharmacological bases should actively carry out clinical pharmacological consultation, and units with conditions should be open to society. For drugs with a narrow scope of treatment, blood concentration monitoring should be carried out in this unit to provide scientific basis for clinical treatment and do everything necessary to ensure that the medication is safe and effective. Information exchange between bases is an extremely important means to promote the development of clinical pharmacology.

(7) Undertake temporary tasks and temporary clinical pharmacological tasks assigned by the Ministry of Health and the Department of Health.