What Are Antiemetics?

Antiemetics are drugs that prevent or reduce nausea and vomiting. Antiemetics inhibit vomiting through different links, including thiazines, antihistamines, and anticholinergics.

Drug Name: Antiemetic
Foreign name: antiemetic drugs
Main indications: Vomiting caused by anticancer radiotherapy and chemotherapy

Main medication contraindications: Not suitable for pregnancy vomiting
Main varieties: Modin
Classification: Thiazines, antihistamines, etc.

Introduction to Antiemetics

Antiemetic drugs

Including the following categories: phenothiazine drugs, such as chlorpromazine, perphenazine, triflurazine, prochlorperazine, etc., mainly inhibit the chemosensitive area of vomiting, and are effective for a variety of vomiting. Antihistamines are commonly used for motion sickness and vomiting, such as Min Ke Jing, An Qi Min, Diphenhydramine, Cheng Hao Ning and so on. anticholinergic drugs, such as scopolamine. Others include metoclopramide (Metoprolol), domperidone (Morbutolin), antieperline, chlorobutanol, brominaprocaine and so on.

The main varieties of antiemetics

Modin, metoclopramide.

Antiemetic Application Principles

First clear the cause of vomiting, remove the cause or treat the cause as much as possible; correct possible metabolic and water and electrolyte disorders; weigh the pros and cons of antiemetics and adverse reactions without other treatments, and consider whether to use .

Antiemetics should not be used for vomiting during pregnancy. Changing the diet, intravenous fluids, and vitamin B6 can be used. If necessary, antihistamines can be given as appropriate.

For vomiting caused by motion sickness, anti-cancer radiotherapy and chemotherapy, preventive medication is effective.

Antiemetics are generally not used to prevent vomiting before surgery, except for ophthalmology and craniocerebral surgery or special circumstances.

Antiemetic use

Nausea and vomiting caused by chemotherapy are one of the most common adverse reactions in cancer patients. At present, there are many drugs for the control of nausea and vomiting caused by chemotherapy, such as phenothiazines, dopamine antagonists, antihistamines, etc., but these drugs have relatively large side effects. Serotonin inhibitors such as Gramisetron (Kangquan, Kateri), Tropisetron (Tropisetron), Ramosetron (Nezia), Azasetron (Azasetron) , Su Luotong) and Dolasetrone, which have not yet been listed in China. Foreign companies such as Glaxo, Novartis, Bristol-Myers Squibb, and Yamanouchi have a series of original research products. After undergoing long-term clinical application, such products have been recognized by the majority of clinicians and have become the mainstream of the international and domestic antiemetic market. Is the best antiemetic for vomiting after chemotherapy.

Classification of antiemetic Chinese medicine

At present, academic circles are generally divided into antipyretics, antipyretics, laxatives, phlegm repellents, humectants, diuretic and dampness medicines, Wenli medicines, qi-eliminating medicines, digestive medicines, insect repellents, hemostatic medicines, and blood circulation and blood stasis medicines. Twenty-one, phlegm relieving cough and asthma medicine, soothing medicine, pacifying liver and wind medicine, resuscitation medicine, tonic medicine, astringent medicine, gush medicine, detoxification, insecticide, dampness and antipruritic medicine, detoxification and saprophytic medicine, etc. class. The representative textbooks of contemporary colleges and universities of Chinese medicine are the planning materials. Famous Chinese medicine expert Dr. Li Jimin believes that Chinese medicine is unique in its antiemetic and anti-inverse properties. Antiemetics should be listed separately in terms of classification.

Antiemetic Research Developments

In the long-term clinical practice, Dr. Li Jimin has continuously researched and concluded that Chinese medicine should be divided into antiemetic drugs, and antiemetic drugs can be divided into warm and antiemetic drugs, heat relieving antiemetic drugs, antireverse antiemetic drugs, and antiemetic drugs. There are four kinds of medicine. The common clinical medicines for warming and stopping vomiting are Evodia rutaecarpa, ginger, Amomum villosum, white cardamom, grass cardamom, galangal, heartwood, etc .; the antipyretic and antiemetic medicines include Zhu Ru, Reed Root, etc .; the antiemetic medicines for anti-emetics include Pinellia, Cloves, rotten flowers, coriander leaves, persimmon pods, sword beans, vermiculite, etc .; anti-emetic medicines include aquilaria, agarwood, and perilla.

When we study medicine, we all serve the treatment of diseases. Everything is done for the clinical treatment of diseases. The curative effect is the overriding problem. The curative effect is the last word. The accurate scientific classification of medicines is conducive to the selection of drugs for clinical applications and to improve the efficacy and curative effect.

Antiemetic medicine

Zhuru is slightly cold, and has the effect of clearing heat and reducing phlegm. Zhuru 10 to 15 grams of decoction drink can cure headaches, vomiting and other symptoms after drinking.

Galangal has a hot and spicy taste, with warming and stopping vomiting, and cold and pain relief. Galangal decoction of 10 to 15 grams can treat drinking too much and get cold and vomiting.

Sophora flavescens has bitterness, dryness and dampness, and has the functions of expelling wind, insects, and diuresis. 10-12 grams of decoction of Sophora Flavescens can be used to sober up.

Schisandra has a sour, sweet and warm taste, which has the effect of constricting the lungs and nourishing the kidneys, regenerating the sweat, astringent essence and stopping diarrhea. Schisandra 10 ~ 12 grams of decoction drink can be hangover.

Gehua is an unopened bud of Gege. It has a sweet taste, is good at detoxifying alcohol, refreshes the spleen, and quenches thirst. Gehua 10 to 15 grams of decoction can cure headaches, dizziness, thirst, and chest fullness caused by excessive drinking.

Nutmeg tastes pungent and warm, has astringent and antidiarrheal, warms the qi and digests the food. Take 10 to 12 grams of nutmeg decoction and drink, which can cure abdominal fullness and vomiting when drunk.

Black plum has a sour, astringent, and flat taste, and has the effects of constricting the lungs, astringent intestines, and promoting jin. Take 30 grams of ume plum decoction to relieve your thirst after drunkenness.

Mulberry has a sweet and slightly cold taste, and has the effects of nourishing yin and nourishing blood and intestinal moistening. When hangover, you can take 150 grams of fresh mulberry juice to drink.

White cardamom has a mild taste, has the effects of dampening the stomach and invigorating the stomach, stopping vomiting at the warmth, and fullness of air. Take 10 to 12 grams of decoction of white cardamom, which can eliminate vomiting caused by drunkenness.

White grass root has a sweet and cold taste, has cooling blood to stop bleeding, clearing heat and diuretic effect. Take 15-30 grams of decoction of white grass root to detoxify the wine.