What Are the Causes of Gastric Cancer?

Gastric cancer genes are prone to form lumps and block passages, causing food to become uncomfortable in the stomach. Patients with gastric cancer have obvious familial aggregation. The survey found that the first-degree relatives (ie parents and siblings) of patients with gastric cancer have an average three times higher risk of gastric cancer than the general population. The more famous family is Napoleon. His grandfather, father, and three younger sisters died of gastric cancer. A total of 7 people, including himself, suffered from gastric cancer.

Gastric cancer genetics

Gastric cancer genes are prone to form lumps and block passages, causing food to become uncomfortable in the stomach. Patients with gastric cancer have obvious familial aggregation. The survey found that the first-degree relatives (ie parents and siblings) of patients with gastric cancer have an average three times higher risk of gastric cancer than the general population. The more famous family is Napoleon. His grandfather, father, and three younger sisters died of gastric cancer. A total of 7 people, including himself, suffered from gastric cancer.

TCM disease name

Gastric cancer genetics

Common locations

stomach

Common symptoms

Food upset

way for spreading

Heredity

Features

Family aggregation

Risk factors for stomach cancer include lack of physical exercise, mental depression, smoking, preference for smoked foods, preference for heavy salt diets, excessive intake of meat,

1. Diffuse gastric cancer is closely related to heredity

Gastric cancer tends to gather in families. Previous studies have suggested that environmental factors may be the main cause of occurrence and prevalence, but genetics and immunity play a role in the formation of gastric cancer. The results of a down-control study of 752 cases of gastric cancer in nine cities including Beijing, Shanghai, Xi'an, and Fuzhou in China show that the incidence of gastric cancer in patients with a family history of tumors is greatly affected by environmental factors, and diffuse gastric cancer is closely related to families. At present, gastric cancer in many countries shows a downward trend. The results of investigation and analysis show that intestinal gastric cancer decreases rapidly over time, while diffuse cancer decreases slowly.

2. Gastric cancer is caused by chromosomal aberrations

The familial genetic phenomenon of cancer is currently thought to be caused by chromosomal aberrations, which are sometimes passed on to offspring, but this inheritance is not a direct cancer inheritance, but an individual's tendency to develop cancer. When the body's immune function is low or defective, it can increase the susceptibility to gastric cancer, and the mutant cells cannot be eliminated in time at the germination stage, resulting in the occurrence of gastric cancer.

3.People with blood type A are more likely to develop stomach cancer

ABO blood group studies have shown that gastric cancer is associated with blood type A, but only with diffuse gastric cancer . Correa reports that 49% of 164 cases of diffuse gastric cancer are type A blood and 38.3%. The association of diffuse gastric cancer with blood type A is a genetic predisposition. Recently, with the application of molecular genetics in human cancer research, people have gradually realized that cancer is the dominant role of activated cellular genes. This is essentially due to mutations in some genes that disrupt the coordination that controls and regulates the growth and development of normal cells, leading to abnormal cell reproduction. However, it is difficult to study the role of genetic factors in the etiology of human gastric cancer, which needs to be further studied.

4. Genetic immunity and gastric cancer

The epidemiological study of gastric cancer suggests that environmental factors may be the main cause of the occurrence and prevalence of gastric cancer, and genetics and immunity also play a certain role in the formation of gastric cancer. Correa classified gastritis into an autoimmune type, a high secretion type, and an environmental type from an epidemiological point of view in 1980. It is believed that autoimmune type is mainly related to the immune mechanism, often with malignant anemia, the lesions mainly involve the gastric fundus and gastric body, and often lead to atrophy of the whole stomach in the later stage, with a genetic tendency. A survey in Colombia found that chronic atrophic gastritis complies with the autosomal-negative genetic rule, and whether the onset is more affected by age and mother. In the population studied, the gene carrier rate of atrophic gastritis is 61%. If the mother is a patient, 72% of children will also develop atrophic gastritis from the age of 0; if the mother is a normal person, the disease will The rate is 41%. It has also been found that malignant anemia with diffuse gastritis is autosomal dominant.

5. Comprehensive tumor treatment system

Correctly understanding and understanding the concept of comprehensive tumor treatment and its scientific connotation have important clinical practical significance, and will help to formulate a reasonable individualized comprehensive treatment plan for each tumor patient to obtain the best treatment effect. To correctly understand and master the connotation of comprehensive tumor treatment, you need to master the following basic points:

Comprehensive treatment of tumors must pay equal attention to the patient's overall condition and the specific characteristics of the tumor in order to avoid one-sidedness and reduce decision errors.

First, when selecting and formulating a comprehensive treatment model, not only pay attention to the short-term effect of killing tumor cells and reduce tumor volume, but also pay attention to the patient's overall condition and long-term effect, pay attention to protect the patient's immune function and the body's righteousness, Conduct a dialectical treatment to avoid the possible consequences of the tumor being "small" or "absent," but the patient's body is "collapsed" or "disabled."

Second, in the process of tumor treatment, we must also pay attention to the characteristics of tumor types, development trends, and biological behaviors. We must not only consider and fear the toxic and side effects of tumor treatment, but also correctly understand the relationship between "positive" and "evil". In the case of strong growth of tumor cells and strong external evils, the best treatment effect will be achieved by taking correct treatment methods to effectively kill tumor cells in time. Otherwise, the tumors that might be cured may be lost. Opportunity.

TCM believes that gastric cancer is a disease of spleen and stomach dysfunction, and its location in the stomach is closely related to liver and spleen. The stomach master accepts and digests, and the spleen and stomach are the basis of acquired metaplasia. Dysfunction of the spleen and stomach, stomach loss and reduction are the pathology of the disease; spleen and kidney yang deficiency, middle coke deficiency cold is the root of the disease. The pathogenesis of gastric cancer lies in the deficiency of stomach yang. First, there are yang deficiency, then qi deficiency, phlegm, blood stasis, and other pathological features, which form a mass and block the passage, causing food to be upset, and even vomiting or ingestion. threw up. The emergence of gastric cancer is a serious threat to the health and life of patients, so how to get rid of the problem of gastric cancer has always been the most concerned by all patients.