What Can Cause Acetone in Urine?

Ketone bodies in urine are a collective term for three different components. They are acetone, acetoacetate, and beta-hydroxybutyric acid. They are intermediate products of fat metabolism in the body. Under normal circumstances, it is rarely generated and cannot be detected by our current routine methods, so the normal human ketone body qualitative test is negative. However, in the case of starvation, impaired glucose metabolism due to various reasons, increased lipolysis, and diabetic acidosis, the rate of ketone body production is greater than the rate of tissue utilization, and ketonemia may occur, followed by ketonuria.

Urine Ketone

Right!

Ketone bodies in urine are a collective term for three different components. They are acetone, acetoacetate, and beta-hydroxybutyric acid. They are intermediate products of fat metabolism in the body. Under normal circumstances, it is rarely generated and cannot be detected by our current routine methods, so the normal human ketone body qualitative test is negative. However, in the case of starvation, impaired glucose metabolism due to various reasons, increased lipolysis, and diabetic acidosis, the rate of ketone body production is greater than the rate of tissue utilization, and ketonemia may occur, followed by ketonuria.

Qualitative test: negative

(1)

Plus sign

mg / dL (mg / dL)

mmol / L (mmol / L)

Trace

5

0.5

+

15

1.5

+ +

40

3.9

+ + +

80

7.8

+ + + +

160

15.6

Ketones may be:

1. Diabetic patients and diabetic acidosis will show a strong positive (+++ or more). At this time, attention should be paid, and toxic coma is prone to occur. Treatment measures should be taken in time.

2. After severe vomiting, diarrhea, chronic malnutrition, hunger, and vigorous exercise.

3 Vigorous vomiting, eclampsia, and digestive disorders in pregnant women due to pregnancy reactions.

When your body cannot use glucose as an energy source, it will use fat to break down to generate energy. At this time, an acid substance called ketone body will appear. If ketone body accumulates too much in the body, it will cause serious consequences, coma. Therefore, diabetics, especially those with type 1 diabetes, should be able to self-monitor urinary ketone bodies in order to detect excessive ketone accumulation in the body in a timely manner.

Urine ketones should be measured in the following cases:

* Please test your urine ketone body when:

Blood sugar over 240mg / dl

When treatment is stopped for various reasons

Cold or cold

Suffer from infectious diseases

Before and after surgery

Vomiting or upset stomach

Pregnancy

Extremely nervous

* Determination method-self-test urine ketone body can use test paper method:

Insert the test paper into the urine sample.

Wait a few seconds as instructed.

Compare the test strip to the standard plate on the package.

Record the test results.

Note: If the urine ketone body is above "++" or 40mg / dl, you should go to the hospital immediately

Urinary ketone body test: Detection of urinary ketone body mainly contains

Please pay attention to it during use: Because both acetone and acetoacetate in the ketone body of urine are volatile, acetoacetate is more easily decomposed into acetone by heat; when the urine is contaminated by bacteria, the ketone body disappears, so the urine must be fresh and promptly submitted for inspection. In order to avoid false negative results or low results due to volatilization or decomposition of ketone bodies; Sensitivity of dry method and ketone powder method are different: the sensitivity of ketone powder method to acetoacetic acid and acetone is 80mg / L and 100mg / L. It is not as sensitive as the test strip method, so there may be differences in results between the two methods of the same pathological specimen, and special attention should be paid when analyzing the results; ketosis caused by different etiologies, the composition of ketone bodies is different, even a patient may have different course of disease, For example, in the nomenclature of early stages of diabetic ketoacidosis, -hydroxybutyric acid, the main ketone body component, has little or no acetoacetic acid. At this time, the measurement result can lead to an underestimation of the total ketone body amount. After the symptoms of diabetic ketoacidosis are alleviated, -hydroxybutyric acid is converted to acetoacetic acid, and the content of acetoacetic acid is increased from the initial acute stage, which is likely to overestimate the condition. Therefore, the inspectors must pay attention to the development of the disease course and analyze the experimental results with the clinician.