What is Congenital Insensitivity to Pain?

Congenital analgesia is a rare congenital disease with clinical features characterized by loss of pain throughout the body and can be complicated by Charcoal arthritis, which has not been reported in the domestic radiological literature.

Congenital analgesia

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Congenital analgesia is a rare congenital disease with clinical features characterized by loss of pain throughout the body and can be complicated by Charcoal arthritis, which has not been reported in the domestic radiological literature.

Chinese name

Congenital analgesia

Foreign name

congenital insensitivity to pain with anhidrosis

Short name

CIPA

Clinical manifestation

Pain loss, life can take care of itself

Attributes

Autosomal recessive disease

Treatment

No clear treatment guidelines

Sprained limbs often cause skin damage or bleeding due to play, but patients cannot detect it because they are painless. Sensory disorders, including pain and temperature, anhidrosis, mental retardation, fever, multiple fractures and infections.

This disease is an autosomal recessive disease. Pain is a feeling of the body. Everyone will be tortured by painful stimuli multiple times throughout his life. A person from head to toe, from the body surface to the internal organs may be affected by external stimuli. Or its own pathological changes to produce different levels of pain. Pain is a signal of injury. Its intensity is closely related to the degree of physical damage. Usually, the body is exposed to noxious stimuli such as acid, alkali, high temperature, low temperature, current, machinery, and violence. Pain is produced when under compression (tumor compression), and nerves are the receptors of human pain. Every part of the human body is densely packed with nerves and their terminals, and nerve impulses can be generated by any stimulation. The nerve endings transmit impulses through the spinal cord to the brain to produce pain. Generally women are more painful than men. This is because female nerve endings are thin and sensitive. A person's mental state and emotional changes can also affect the sensitivity to pain, such as fear, Anxiety, tension, and anger can aggravate the pain of patients. Conversely, pain is relieved to varying degrees when you are in a good mood, relaxed, or cared for by your family. In addition, due to different pain locations, patients' response to pain is also different. For example, if a head injured person thinks that it may be life-threatening, he feels unbearable pain. Environmental factors also affect the body s response to pain to varying degrees.

Dearborn first reported in 1932 that according to Thrush statistics, 45 cases of the disease were reported in the literature from 1932 to 1970, plus 4 cases in the same family that Thrush himself reported in 1973, a total of 49 cases.

One case was reported as follows: Jin X, female, 7 years old, complained of swelling in the right ankle joint that did not heal for more than 2 months, but there was no movement disorder or any pain. At 6 months,

There is no clear treatment strategy.

No detailed prevention plan

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