What is desipramine?
desipramine is a drug that is used in the treatment of depression. Unlike some antidepressants that focus on the inhibition of serotonin reuptake in the brain, desipramine acts inhibition of norepinephrine reuptake. The drug is sold under several different brands, including pertophrane and norpramine. Although this medicine, which was sensitively used in the treatment of depression, was usually used only when the patient has a negative reaction to several antidepressants that focus on serotonin reuptake.
classified as tricyclic antidepressant, desipramine works by allowing any amount of norefinephrine produced in the brain to stay longer in the system. As with other types of reuptake inhibitors, the suspension of the reuptake process leads to an increased mood for the patient, which gradually facilitates individuals from depression and start to re -capture interest in hobbies, family and life in general. The exact dose that is administrated will dependt on the severity of depression, as determined by a qualified healthcare worker.
As with most antidepressants, desipramine takes some time to work into the system and start to have effect. The required time depends on the individual and can range from a few weeks to three or four months. Rarely is the effect of a sudden or dramatic nature of the drug. Rather, the individual begins to feel a slow but consistent recession of the constant feelings of worthlessness, lethargy and general lack of interest, which are common symptoms of depression.
It has also been found that desipramine is effective as a means of treating recurring pain by blocking signals of pain in brain. There is also evidence that the drug can also be useful with cases of attention disorder., along with most drugs, desipramine does bear the risk of some side effects. Some research suggests that the use of a medicine for a longer period of time mayincrease the chance to develop breast cancer. As with any antidepressant, the drug can cause the opposite effect and cause depression to deepen. For this reason, it is important to report any changes in the mood immediately, especially if they include suicide thoughts.
Although it is no longer considered to be the first defense line in terms of the treatment of depression, desipramine can often be very useful to people who do not respond well to any type of drug that inhibits serotonin reuptake. The gradual weaning of drugs can usually be achieved with a fewer side effects if the attending physician closely monitors the tapering period. For people who try other types of antidepressants and find that they either do not help or worsen symptoms, desipramine may be the ideal form of treatment.