What Is Lip Cancer?

Lip cancer is mainly squamous cell carcinoma, and adenocarcinoma is rare. Occurs mostly in the lower lip, often in the mucosa of the lip red margin between the middle and outer 1/3 of the lower lip. Early is a herpes-like crusted mass, or a localized thickening of the mucosa, followed by crater-like ulcers or cauliflower-like masses. Lip cancer grows slowly and generally has no conscious symptoms. Later, the tumor spreads to the surrounding skin and mucous membranes, and infiltrates into deep muscle tissues at the same time; it can spread to the oral vestibules and jaws. [1] [2]

Zhang Lei (Deputy Chief Physician) Department of Maxillofacial Surgery, Peking University Stomatological Hospital
Guo Chuanyu (Chief physician) Department of Maxillofacial Surgery, Peking University Stomatological Hospital
Carcinoma of the lip is a cancer that occurs in the mucosa of the red lips. According to the UICC classification, the inner lip mucosa should be buccal mucosa cancer; those with dermal origin should be classified as skin cancer; lip cancer should be limited to the primary cancer of the lip red mucosa. In view of this, lip cancer has been separated from oral cancer; however, in a broad sense, there are also people who claim to classify lip cancer as oral cancer.
Western Medicine Name
Lip cancer
English name
carcinoma of the lip
Affiliated Department
Department of Physiology-Stomatology
Disease site
Lip
The main symptoms
Herpes-like crusted mass with localized mucosal thickening, crater-like ulcers, cauliflower-like mass
Disease classification
Oral disease
Disease code
ICD-9: 140.902 ICD-10: C00.901

Clinical manifestations of lip cancer

Lip cancer is mainly squamous cell carcinoma, and adenocarcinoma is rare. Occurs mostly in the lower lip, often in the mucosa of the lip red margin between the middle and outer 1/3 of the lower lip. Early is a herpes-like crusted mass, or a localized thickening of the mucosa, followed by crater-like ulcers or cauliflower-like masses. Lip cancer grows slowly and generally has no conscious symptoms. Later, the tumor spreads to the surrounding skin and mucous membranes, and infiltrates into deep muscle tissues at the same time; it can spread to the oral vestibules and jaws. [1] [2]

Lip cancer disease metastasis

Lower lip cancer often metastasizes to sub-condylar and submandibular lymph nodes; upper lip cancer metastasizes to front ear, submandibular, and cervical lymph nodes. The metastasis of the upper lip is earlier and more common than the lower lip. Lip cancer metastasis is generally less common than other oral cancers, and the metastasis time is relatively late. [1] [2]

Lip cancer disease treatment

Early cases have good results regardless of whether surgery, radiation therapy, laser treatment or hypothermia is used; but advanced cases and patients with lymph node metastasis should be treated with surgery. Clinically, non-metastatic lip cancer can also be performed with one or both scapula and superior scapula neck dissection, but if clinically proven metastasis, cervical dissection is required. After the primary lesion is removed, it can be immediately restored with adjacent tissue flaps. [1] [2]

Lip cancer disease control information

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