What Is Lupus Cerebritis?

Systemic lupus erythematosus can be combined with damage to the central nervous system and peripheral nervous system, and can cause a variety of neurological and psychiatric symptoms. Among them, the neurological and psychiatric symptoms of the central nervous system are called lupus encephalopathy.

Lupus brain

Systemic lupus erythematosus can be combined with damage to the central nervous system and peripheral nervous system, and can cause a variety of neurological and psychiatric symptoms. Among them, the neurological and psychiatric symptoms of the central nervous system are called lupus encephalopathy.

Clinical manifestations of lupus brain

The clinical manifestations of lupus encephalopathy are diverse and include neurological and psychiatric symptoms.

Epilepsy is the most common damage to the nervous system, followed by cerebrovascular disease, cranial nerve palsy, intracranial hypertension, aseptic meningitis, and transverse inertia spondylitis. In the first 5 years of onset of lupus, the incidence of cerebrovascular accidents is very high. In the first year, patients with anti-phospholipid antibodies that are 6.6% larger are more likely to occur. About 10% of patients with lupus encephalopathy have cranial nerve abnormalities.

Mental abnormalities are mainly manifested as psychotic reactions, such as audition hallucinations, delusions, stiffness, fear, and sense of control: organic encephalopathy syndrome is manifested as disturbance of consciousness, decreased orientation, distracted attention, poor memory, and abnormal behavior; emotions Disorders and neurotic reactions, such as hypomania, depression, anxiety, hysteria, and suspected illness. About 60% of people with mental disorders with lupus encephalopathy are positive for anti-ribosomal P protein antibodies, indicating that mental disorders are related to anti-P protein antibodies. Monitoring anti-ribosomal P protein antibodies is helpful to distinguish them from other causes of mental disorders.

At present, it is believed that among the many clinical manifestations, the most valuable manifestations for the diagnosis of this disease are epilepsy, psychiatric symptoms, transverse myelitis, stroke, transient ischemic attack and aseptic meningitis.

Lupus brain treatments

1, hormone shock therapy, such as the application of methylprednisolone intravenous drip.

2. Traditional Chinese medicine mainly includes Qingxin Kaiqiao, cooling blood and detoxification. Angong Niuhuang Wan, Xingnaojing and Qingkailing are selected.

3, dehydration therapy: such as the use of hypertonic dehydrating agents, 20% mannitol, 50% glucose solution, hypertonic saline and so on. Serum albumin and concentrated plasma are colloidal dehydrating agents, which are slow in action and expensive, and can be selected as appropriate. Diuretic dehydrating agents, such as furosemide, are fast and strong.

4. General treatment can be symptomatic treatment: bed rest, keep the urination unobstructed; control fluid intake, pay attention to water and electrolyte balance; for severe headache, excitement, and irritability, choose analgesic sedatives as appropriate; pay attention to protect brain cells, especially in coma Those who are in the state should be given drugs that promote brain cell metabolism and body recovery, such as adenosine triphosphate, coenzyme A, cytochrome C, cerebrolysin, citicoline, and B vitamins.