What Is Ossification?

Subject: Biology

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Refers to the formation or transformation into bone.

Refers to the process of bone tissue formation in the narrow sense refers to the calcification of osteoblasts (osteoblasts) in the bone matrix.

There are two ways:

(1) Cartilageinous ossification (endochondral ossification): The glass cartilage tissue is first formed and then replaced by bone tissue. It is a type that can be seen in most bones. The bones produced according to this type are called cartilage bone and replacement bone.

(2) connective tissue ossification (fibrous ossification) or fibrous ossification (fibrous ossification): within the fibrous connective tissue, the type of bone tissue directly formed, can be seen in some skulls. The bones produced by this type are called connective tissue bones, periosteum bones, capped bones, and the like. It is unclear whether osteoblasts in these two forms of osteogenesis undergo secondary transformation through chondroblasts or fibroblasts, or are directly differentiated from surrounding undifferentiated cells. Osteoblasts are gradually embedded in collagen fibers formed by themselves and accompanied by a matrix of calcium deposits, and become osteoclasts. While osteoblasts are ossifying, on the other hand, osteoclasts with multinucleated cells of the same source destroy fibers and matrix through phagocytosis. Due to two opposite activities, at the same time through bone growth and reconstruction, the bone is compacted , And adjust the calcium and phosphorus levels in the blood. Osteoclast stimulation and inhibition are related to parathyroid hormone and calcitonin, respectively.

The formation of bone, in the membranous bone or

After the emergence of most adults, the body wall hardens quickly. This process is called ossification.