What Is Phaeohyphomycosis?
Fungi are extremely widespread in nature and are common in human mouth, stomach, and intestines. Usually it is a harmless parasitic state, but when the gastric mucosa is impaired by local blood circulation or the body's immunity is weakened, the fungus can cause gastritis or ulcers, and may even have perforation and sinus formation.
Basic Information
- Visiting department
- Basic surgery
- Common locations
- stomach
- Common causes
- Candida albicans and Aspergillus, Actinomyces infection
- Common symptoms
- Similar to gastritis, gastric ulcer or cancer
Causes of gastric mycosis
- The main species that can cause gastric mycosis are Candida albicans and Aspergillus, actinomycetes are relatively rare. It has been reported that local blood circulation disorders or decreased immunity of the gastric mucosa may be the basis for the onset of gastric mycosis. A diphtheria-like pseudomembrane is often formed on the gastric mucosa in the early stage, and then it can develop into an ulcer and sometimes embolization of submucosal blood vessels. The ulcers formed can be singular or plural, sometimes involving the entire stomach wall, and usually do not form perforations.
Clinical manifestations of gastric mycosis
- The disease has no specific clinical manifestations, and the manifestations can be difficult to distinguish like gastritis, gastric ulcer or cancer. X-rays are usually not helpful for diagnosis. Although a large number of fungi are often found in vomit or gastric contents, gastric fungal diseases are rare, and there are many opportunities to find fungi in gastric contents. Therefore, simply detecting fungi cannot be diagnosed as gastric fungal diseases.
Gastromycosis examination
- Pathological examination of the biopsy is the basis for the diagnosis of the disease. The section showed the presence of false membranes, and microscopic examination revealed mycelia.
Gastromycosis diagnosis
- The clinical manifestations are non-specific, and the possibility of the disease should be considered after excluding gastritis, gastric ulcer or cancer. Pathological examination can confirm the diagnosis.
Differential diagnosis of gastric mycosis
- The disease needs to be distinguished from diseases such as gastritis, gastric ulcer and gastric cancer.
Gastromycosis treatment
- In recent years, antifungal drugs have developed rapidly, and the treatment of gastric mycosis has greatly changed. Patients with bleeding or perforation due to gastric mycosis should consider emergency surgery. Treatment principle: Application of antifungal drugs and symptomatic supportive treatment.
- Dietary attention
- Eat regularly and quantitatively, eat less frequently, and eat soft, digestible and non-irritating food. Remove lesions, quit smoking, alcohol, strong tea, etc., and use drugs that stimulate the stomach with caution.
- 2. Drug treatment
- (1) Antibiotics such as berberine, streptomycin, gentamicin, and antifungal drugs should be taken before meals, and 7 to 14 days is a course of treatment.
- (2) Acid inhibitors are suitable for patients with normal or high gastric acid, such as aluminum hydroxide, H 2 receptor antagonists (cimetidine, ranitidine, famotidine, etc.) and sucralfate.
- (3) Proton pump inhibitors such as omeprazole, taken before breakfast, are suitable for patients with type A atrophic gastritis.
- (4) Antiemetic drugs such as metoclopramide, taken before meals and before bedtime.
- (5) Gastrointestinal power medicine, suitable for patients with abdominal distension, food and bile reflux.
- (6) Digestive aids are suitable for patients with low gastric acid, no gastric acid or ineffective antacids. Pepsin and 1% dilute hydrochloric acid are given after meals.
- (7) Prednisone is suitable for patients with type A chronic atrophic gastritis, once a day, orally, one month as a course of treatment.
- (8) Anemia should be corrected for gastritis with anemia.