Why Shouldn't I Pop a Cold Sore?
Cold sore is an acute herpestic skin disease caused by the herpes simplex virus. Humans are the only natural host of herpes simplex virus. This virus exists in the blister fluid, saliva, and feces of patients, restorers, or healthy carriers. It is mainly transmitted by direct contact and can also be transmitted through tableware contaminated with saliva. Indirect infection.
Herpes on the lips
- Cold sore is an acute herpestic skin disease caused by the herpes simplex virus. Humans are the only natural host of herpes simplex virus. This virus exists in the blister fluid, saliva, and feces of patients, restorers, or healthy carriers. It is mainly transmitted by direct contact and can also be transmitted through tableware contaminated with saliva. Indirect infection.
Herpes on the lips 2. Causes
- The disease is caused by the herpes simplex virus of the DNA virus. Human herpes simplex virus is divided into two types, herpes simplex virus type I (HSV-I) and herpes simplex virus type II (HSV-II). Type I mainly causes infection of skin and mucous membranes (oral mucosa) and organs (brain) outside the genitals. Type II mainly causes skin and mucous membrane infections in the genital area. The virus enters the body through the respiratory tract, oral cavity, genital mucosa, and damaged skin, and resides in the human normal mucosa, blood, saliva, and sensory ganglion cells. When the body's resistance decreases, such as fever, gastrointestinal dysfunction, menstruation, fatigue, etc., the latent HSV in the body is activated and becomes ill.
Lip herpes III. Clinical manifestations
- Herpes simplex virus infection: Herpes simplex virus, the infection caused by the number of CD4T lymphocytes, the formation of ulcerative lesions on the lips, genitals, perianal area, herpes ulcer (extensive skin erosion) and other refractory diseases, pain is obvious You can also see herpes pneumonia and herpes encephalitis.
- 1. Erythema and blisters appear on the lips, around the nostrils, and on the cheeks, and feel itching and burning.
- 2. There are erythema, blisters on the vulva, and itching sensation.
Herpes on the lips
- 1. Mainly moderate or above cellular immune deficiency includes: CD4 + T lymphocyte depletion: T lymphocyte function declines, peripheral blood lymphocytes significantly decrease, CD4 <200 / l, CD4 / CD8 <1.0, (1.25-2.1 in normal people) ), Late-onset allergy negative skin test, low response to mitogen stimulation.
- 2. B lymphocyte dysfunction: polyclonal hyperglobulinemia, formation of circulating immune complexes and autoantibody formation.
- 3. Natural killer cells (NK cells) activity decreased.
Herpes on the lips
- Local treatment
- (1) 3% boric acid solution or normal saline for those with obvious blisters or local swelling, apply wet until the damage subsides.
- (2) Apply 1% -2% gentian violet liquid to the affected area twice a day.
- (3) Apply 3% acyclovir ointment topically several times a day.
- (4) Apply 0.5% neomycin ointment topically.
- 2. Systemic treatment
- (1) Gamma globulin, intramuscular injection, once every other day, a total of 3 to 4 times.
- (2) Cimetidine: Orally, 3 to 4 times a day for 5 consecutive days.
- (3) Oral vitamin C, vitamin B2 or multivitamin B.
- (4) Acyclovir: Orally, 5 times a day. Severe patients can be administered intravenously. Acyclovir is added to a 5% glucose injection intravenously, 2 to 3 times a day for 5 days.
- (5) antibiotics (penicillin, vanguardin) for secondary infections.