What is microchimerism?

microchimerism is a phenomenon in which the body of the body contains a small number of cells from another organism. Unlike tetragametic chimerism, microchimerism is obtained. On the other hand, in tetragametic chimerism, there is an innate feature when two non -identical zygots or blastocysts are fucking and develop into a single organism composed of two cell populations, each with its own different genes. Microchimerism occurs in many species, including humans. Cells from the fetal immune system can enter the mother via the placenta, where they can survive and continue to be reproduced by mitosis. In some cases, the descendants of these fetal cells remain in the mother decades later. Otherwise, the same process may result in the immune cells of mothers living in the fetus, although it is less common. It may also result from organs and blood transfusions.

There is some research suggesting that microchimerism can cause some autoimmune disorders, jaKo is lupus. The presence of maternal immune cells was accused of some autoimmune diseases suffered from children, such as youthful dermatomyositis. Some cases of systemic sclerosis, a disease that damages the skin, joints and some internal organs, may be caused by immune cells of the fetus living in the mother and some studies have combined the presence of fetal immune cells with breast cancer. Autoimmune disorders are more common in women than in men and the effects of fetal cells have been designed as a possible reason.

However, the consequences of research in this area are still ambiguous. Frequent presence of fetal or parent immune cells in tissues affected by these diseases may indicate that they cause or contribute to the disease, but it could also mean that foreign cells are present because you are arpomating to fight disease or alleviate damage. Therefore, it was also assumed that someMicrochimerism can be in particular beneficial.

In some animals such as cattle, it is common for placenta to join in the womb and share blood circulation. As a result, cells can easily pass between fraternal twins in the womb, resulting in microchimerism. In the case of fetus male and female fetus, in this way, the exchange of sexual hormones during the development that the woman partially masculine. This prevents the normal development of reproductive organs and leads to what is called a Mason, a sterile female, which may have partly male properties. The presence of microchimerism is used to confirm that a woman is freemartin because her blood will contain cells with male genetic material that originated in her twin

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