Is it safe to combine methadone and oxycodone?

classified as opiate analgesics, both methadone and oxycodone are drugs used to treat medium to severe pain. The combination of these drugs may bear the risks of increased side effects that may be fatal in some cases, for example in respiratory depression. In some cases, however, both drugs can be safely combined under the supervision of a doctor to treat specific cases of pain. However, due to potential safety risks, they should not be mixed unless the doctor does not advise. The effects of methadone can take 24 to 36 hours, which is suitable for the treatment of chronic pain. Oxycodone usually takes approximately six to eight hours and approximately 12 hours in the formulation of prolonged release in its formulation. Depending on its formulation, it can be used to treat acute pain that suddenly occurs or chronic pain.

Doctors can use a combination of opioid analgesics to treat certain health conditions. Conditions that include the basic level of chroNic pains that must be controlled, along with acute pain that may occur unexpectedly, often include a combination of long -acting and short -acting opiates. In this case, doctors may prescribe methadone and oxycodone simultaneously, with methadone being taken daily for chronic pain and oxycodone used as needed when acute pain occurs.

The side effects of these drugs often increase when combined. For this reason, methadone and oxycodone should only be mixed under the supervision of a doctor. The common side effects resulting from the use of some or both drugs may include nausea, stomach discomfort and drowsiness. Large doses of opioids can lead to more serious side effects, especially respiratory depression or BRSOT difficulty. In severe cases, respiratory depression may be fatal and the mixing of opioids increases the chance that this effect is developing.

Interaction of the healingIva also increases when mixing methadone and oxycodone. The use of both drugs at the same time increases the risk of potentially dangerous sedation combined with other depressed central nervous system remedies (CNS) such as alcohol, benzodiazepines and sleeping pills. Some blood pressure medicines may also have increased reactions with a combination of these drugs. Both painkillers can be addictive and the potential of addiction can be much greater when they are together, which is another reason why a doctor should monitor any combination of both.