Is it Safe to Take Cetirizine in Pregnancy?

Cetirizine dihydrochloride drops are a clear, colorless liquid. Cetirizine dihydrochloride is an H1 receptor antagonist and has no obvious anticholinergic or anti-serotonin effects. Within the effective dose range, cetirizine dihydrochloride does not cause drowsiness or behavior changes This can be explained by the inability of cetirizine dihydrochloride to cross the blood-brain barrier. It is suitable for the treatment of seasonal rhinitis and conjunctivitis, long-term allergic rhinitis, pruritus and urticaria caused by allergies.

Cetirizine dihydrochloride drops

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Cetirizine dihydrochloride drops are a clear, colorless liquid. Cetirizine dihydrochloride is an H1 receptor antagonist and has no obvious anticholinergic or anti-serotonin effects. Within the effective dose range, cetirizine dihydrochloride does not cause drowsiness or behavior changes This can be explained by the inability of cetirizine dihydrochloride to cross the blood-brain barrier. It is suitable for the treatment of seasonal rhinitis and conjunctivitis, long-term allergic rhinitis, pruritus and urticaria caused by allergies.
Drug Name
Cetirizine dihydrochloride drops
Foreign name
Cetirizine Dihydrochloride Oral Drops
Molecular weight
461.8
Main ingredients
Cetirizine dihydrochloride
[Drug name] Cetirizine dihydrochloride drops
[Commodity name] Xian Teming
[English name] Zyrtec
[English name] Cetirizine Dihydrochloride Oral Drops
[Chinese Pinyin] Er'yansuan Xitiliqin Diji
[Main ingredients] The main ingredient of this product is cetirizine dihydrochloride
[Molecular weight] 461.8
[Character] This product
[Pharmacology and toxicology] Animal experiments prove that in clinical pharmacology,
[Usage and Dosage] Recommended for adults and children over 1 year. Adults: In most normal cases, the recommended dose is 1 ml (10 mg, about 20 drops) daily, orally. From the indication of treatment of this product, it is recommended to take this medicine with a small amount of liquid during dinner. If the patient is sensitive to adverse reactions, take it twice a day in the morning and evening, 0.5ml (5mg, about 10 drops) each time. When using the drops, first open the bottle cap according to the icon on the bottle cap, and then the bottle mouth goes down vertically, and the liquid medicine will drip out. Children over 6 years: Take 0.5ml (5mg, about 10 drops) in the morning and evening or 1ml (10mg, about 20 drops) once a day. Children 2-6 years old: Take 0.25ml (2.5mg, about 5 drops) each morning and evening or 0.5ml (5mg, about 10 drops) once a day. Children 1-2 years: Take 0.25ml (2.5mg, about 5 drops) in the morning and evening. Children under 1 year of age: Although there are clinical data on cetirizine for infants over 6 months to 1 year of age, the relevant evaluation has not been completely completed. If you need to use it, please follow your doctor's advice and use it with caution. Elderly patients: elderly patients with normal renal function, refer to the recommended adult dose. For elderly patients with renal insufficiency, see Recommended Dose for Patients with Renal Insufficiency. Patients with renal insufficiency: It is recommended to take the recommended dose in half. That is: the recommended dose for adult or elderly patients is 0.5ml (5mg, about 10 drops) daily, orally. Children over 6 years: Take 0.25ml (2.5mg, about 5 drops) in the morning and evening or 0.5ml (5mg, about 10 drops) once a dayChildren 1-6 years: 0.25ml (2.5mg, about 5 drops) once a day ). Patients with liver dysfunction: If there is no symptom of renal dysfunction at the same time, there is no need to adjust the dosage. Oral drops: 20 drops (1ml) = 10mg 10 drops (0.5ml) = 5mg 5 drops (0.25ml) = 2.5mg
[Adverse reactions] Patients have occasionally reported mild and transient side effects. Such as headache, dizziness, drowsiness, agitation, dry mouth, and upset stomach. In controlled psychological experiments, cetirizine dihydrochloride had a similar effect on sedation as placebo. Patients have occasionally reported minor and transient adverse reactions. Such as headache, dizziness, drowsiness, agitation, dry mouth, and upset stomach. In controlled psychological experiments, the effect of this product on sedation is similar to that of placebo. Rare reports of allergic reactions.
[Caution] At the therapeutic dose, this product will not strengthen the alcohol effect (at a blood concentration of 0.8 grams per liter), but care must be taken. Driving or operating machinery: No change in alertness or response time has been demonstrated in healthy volunteers taking 20 or 25 mg daily. However, patients are advised not to exceed these doses.
[Medication for pregnant women and lactating women] Animal teratogenicity tests have shown no teratogenic effects, but for prevention, cetirizine dihydrochloride should not be administered to pregnant women from the first trimester to the third trimester, nor should it be used by nursing women. .
[Children's medication] See [Usage and dosage].
[Medication for Elderly Patients] For elderly patients with normal renal function, please refer to [Usage and dosage] for adult usage and dosage. For elderly patients with renal insufficiency, please see [Usage and Dosage] for usage and dosage of patients with renal insufficiency.
[Drug interactions] There have been no reports of cross effects with other drugs, but be careful when taking sedatives (hypnotics) at the same time.
[Contraindications] It is contraindicated in those who are allergic to any component of the medicine. Disabled in patients with severe renal insufficiency (creatinine clearance less than 10ml / min).
[Drug overdose] Oral administration of 5ml (50mg) can cause drowsiness. So far, there is no special antidote, and in the case of large overdose, gastrointestinal lavage should be performed as soon as possible. In addition to general emergency supportive care, all vital parameters must be monitored regularly.
[Specifications] (1) 5ml: 50mg; (2) 10ml: 100mg
[Packaging] Glass bottle; 5ml / bottle / box; 10ml / bottle / box.
[Storage] Store at room temperature (15-25 ° C), please keep out of reach of children.
[Validity] 5 years

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