Is it safe to take in pregnancy?
Naproxen is a commonly used painkiller that is part of a family of drugs known as non -steroidal anti -inflammatory drugs (NSAIDs). These drugs work by reducing protein activity known as enzymes that are involved in an inflammatory response. Like many drugs, there are concerns about taking naproxen during pregnancy. This drug can sometimes be used safely during pregnancy, but there are restrictions that are necessary to ensure the health of the mother and the child.
Potentially the use of napxen in pregnancy can damage the fetus. For this reason, doctors recommend that this medicine is not used in the last trimester of pregnancy, even during childbirth. This medicine can also go into breast milk, so mothers should not take their baby during this time.
Even in healthy individuals, this medicine may pose a significant risk to the heart and the cardiovascular system. This risk represents naproxen in pregnancy can be reinforced as shown in some clinical researchIn one study, a mother who used 250 milligrams (mg) of this medicine for early work after 30 weeks gave birth to twins who showed signs of emergency at birth.
The drug levels were measured in infants and it was found to be at dangerous levels. Both infants suffered from pulmonary hypertension and one died shortly after birth. It was concluded that naproxen inhibited the creation of certain proteins in infants and caused a hypertensive crisis in connection with the stress of birth.Animal studies revealed another danger of taking naproxen during pregnancy. Reduced body weight at birth, higher fetal death and increased levels of fetal abnormalities were associated with this drug. These abnormalities were very different on the basis of the case, but included several formities with fatal or lifelong consequences, such as molten vertebrae, heart defects and missing lobes. Problems of creating differentH bones were also associated with the use of naproxen during pregnancy.
studies on people have not been conducted in terms of abnormality or mortality rate, but research suggests that the use of naproxen can extend working hours. For this reason, he should usually avoid him during the third trimester of pregnancy. Previously, during pregnancy, it should only be used only if no alternative medicines are available and minimal risk can be determined.