Is there a connection between simvastatin and weight gain?
Clinical studies have not found any link between simvastatin and weight gain. However, some people report weight gain directly after taking the drug. Although this may preliminarily indicate the link between the increment of drug and weight, it is generally considered to be related to factors other than the drug itself. Clinical studies are designed to reduce variables that could affect the results, and they consistently found that simvastatin and weight gain are not related. It is worth noting that the insufficiently active thyroid gland can cause weight gain and high cholesterol, for which Simvastatin is often prescribed.
High cholesterol levels can lead to many conditions, including heart disease and atherosclerosis, which is characterized by narrower and harder arteries. There are two types of cholesterol, and these can simply be considered "good" cholesterol and "bad" cholesterol. "Good" cholesterol or lipoprotein with high density (HDL), removes cholesterol from the blood and takes it backto Liver, which protects from possible negative results of high cholesterol. The "bad" cholesterol or lipoprotein with low density (LDL) is responsible for all the negative effects of cholesterol because it clogs arteries.
Simvastatin blocks the effects of the enzyme of HMG-COA reductase, which is responsible for creating LDL cholesterol. Cholesterol levels in the liver are reduced, forcing the liver to remove even more from the blood, reducing the risk of conditions such as heart disease. Like this, Simvastatin also reduces the amount of triglycerides in the blood, which are other harmful fats in the body. All these facts are associated and prove that the connection between simvastatin and weight gain is unlikely. Poor diet is a common cause of high cholesterol, which is prescribed for treatment, so if the patient's diet does not change, the weight will continue to interest when taking the drug.
UncooledThe thyroid gland causes weight gain in many patients, and as a result, LDL cholesterol levels often increase. This can lead to a doctor who prescribes simvastatin to patients suffering from insufficient thyroid gland. If the patient's diet does not change when he begins to take the medicine, the weight gain is likely to continue with the insufficient thyroid. This can lead to creating some erroneous links between simvastatin and weight gain. It has been found that other "statins" cause weight gain in some cases, but medical science does not consider it a link between simvastatin and weight gain.