What Are Chloramphenicol Eye Drops?

Chloramphenicol eye drops are indicated for the treatment of eye infections such as trachoma, trachoma, Escherichia coli, Haemophilus influenzae, Klebsiella Conjunctivitis, keratitis, blepharitis, etc.

Chloramphenicol eye drops are indicated for the treatment of eye infections such as trachoma, trachoma, Escherichia coli, Haemophilus influenzae, Klebsiella Conjunctivitis, keratitis, blepharitis, etc.

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Drug Name

Chloramphenicol eye drops

Drug type

Prescription drugs, topical drugs, essential drugs

Use classification

Other ophthalmic drugs

Chloramphenicol eye drops ingredients

Chemical name: D-threo-(-)-N- [- (hydroxymethyl) --hydroxy-p-nitrophenethyl] -2,2-dichloroacetamide.
Chemical Structure:

Molecular formula: C ₁₁ H ₁₂ C1 ₂ N ₂ O ₅
Molecular weight: 323.13
Excipients contain sodium hyaluronate.

Chloramphenicol eye drops properties

This product is a colorless or almost colorless clear liquid.

Chloramphenicol eye drops indications

For the treatment of eye infections caused by E. coli, Haemophilus influenzae, Klebsiella, Staphylococcus aureus, hemolytic streptococcus and other sensitive bacteria, such as trachoma, conjunctivitis, keratitis, blepharitis .

Chloramphenicol eye drops specifications

5ml: 12.5mg

Chloramphenicol eye drops

In the eyelid, 1 to 2 drops at a time, 3 to 5 times a day.

Chloramphenicol eye drops adverse reactions

May have eye irritation, allergic reactions, etc.

Chloramphenicol eye drops contraindications

Those who are allergic to this product are prohibited.

Precautions for chloramphenicol eye drops

1. Large-scale long-term use (more than 3 months) can cause optic neuritis or optic papillitis (especially in children). Patients who use this product for a long time should make an eye examination in advance, and pay close attention to the patient's visual function and symptoms of optic neuritis, and discontinue the drug once it appears. Take vitamin c and vitamin b together.
2. Do not touch the mouth of the bottle during eye drops. Tighten the bottle cap after use. Do not let the mouth contact the skin to avoid contamination.
3. It can be used for up to four weeks after activation.

Chloramphenicol eye drops for pregnant and lactating women

Although this product is used topically, chloramphenicol has a severe bone marrow suppression effect. Pregnant women and lactating women may cause serious adverse reactions in newborns and lactating infants. Therefore, pregnant women and lactating women should be used with caution.

Chloramphenicol eye drops for children

Newborns and preterm infants are disabled.

Chloramphenicol eye drops for elderly

This experiment was not performed and there are no reliable references.

Chloramphenicol eye drops drug interactions

Antagonism can occur when combined with macrolide antibiotics such as lincomycin or erythromycin, so it should not be used in combination.

Chloramphenicol eye drops overdose

This experiment was not performed and there are no reliable references.

Chloramphenicol eye drops pharmacology and toxicology

Pharmacological effects:
This product is a chloramphenicol antibiotic. It has a broad-spectrum antimicrobial effect in vitro, including aerobic Gram-negative and Gram-positive bacteria, anaerobic bacteria, Rickettsia, Borrelia, and Chlamydia.
Bactericidal to the following bacteria: Haemophilus influenzae, Streptococcus pneumoniae, and Neisseria meningitidis. It has only antibacterial effect on the following bacteria: Staphylococcus aureus, Streptococcus pyogenes, Streptococcus grass green, Group B hemolytic streptococcus, E. coli, Klebsiella pneumoniae, Proteus mirabilis, Salmonella typhi, Paratyphoid Anaerobic bacteria such as Salmonella, Shigella, Bacteroides fragile. The following bacteria are generally resistant to chloramphenicol: Pseudomonas aeruginosa, Acinetobacter, Enterobacter, Serratia marcescens, Indole-positive Proteus, Methicillin-resistant Staphylococcus, and Enterococcus. This product is a bacteriostatic agent. Chloramphenicol is fat-soluble, diffuses into the bacterial cells, and can be reversibly bound to the 50S subunit of the bacterial ribosome, which hinders the growth of the peptide chain (probably due to the inhibition of the transpeptidase), thus inhibiting the peptide chain Formation, thereby preventing protein synthesis.
Toxicology research:
This experiment was not performed and there are no reliable references.

Chloramphenicol eye drops pharmacokinetics

This experiment was not performed and there are no reliable references.

Chloramphenicol eye drops storage

Shaded, sealed and stored in a cool place (not exceeding 20 ° C).

Chloramphenicol eye drops packaging

Low-density polyethylene medicinal eye drops in bottles, 5ml / piece, one per box or two per box

Chloramphenicol eye drops expiration date

12 months.

Chloramphenicol eye drops

"Chinese Pharmacopoeia" 2010 edition two ^[1]