What Are First-Generation Antipsychotics?
[1] Antipsychotic drugs are also known as neuroleptics. Is a group of drugs used to treat schizophrenia and other psychotic disorders. The usual treatment dose does not affect the patient's intelligence and consciousness, but can effectively control the patients' psychomotor symptoms such as psychomotor excitement, hallucinations, delusions, hostile emotions, thinking disorders and abnormal behaviors.
Antipsychotics
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- There are more than 40 types of antipsychotic drugs used clinically, of which phenothiazines, thia anthracenes, butyrylbenzenes,
- 1. Indications: mainly used for the treatment and prevention of schizophrenia
- Antipsychotics can produce side effects in many ways, which can vary depending on the type, dose, or individual patient, but most have common side effects, some appearing short-term after administration, and some appearing after long-term administration.
- 1. The side effects caused by the anticholinergic and antiadrenergic effects of the drug include dry mouth, blurred vision, constipation,
- It is mainly used to treat schizophrenia and prevent the recurrence of schizophrenia and control manic episodes. It can also be used for other non-organic or psychiatric symptoms.
- A group of drugs that are mainly used to treat schizophrenia and other mental illnesses. Chlorpromazine is the representative of this class of drugs. More commonly more than 10 perphenazine, haloperidol, and clozapine are used. There is no significant difference in the efficacy of each drug. Drug treatment is simple and effective, and it is the preferred treatment for mental illness. It is easily absorbed after oral administration and is metabolized in the liver. It is mainly excreted by urine, and a small amount is excreted by bile, feces and milk. It has a significant effect on positive mental symptoms such as hallucinations, delusions, and agitation. It is not effective on poor thinking, emotional apathy, and lack of will activity. Serious heart, liver and kidney diseases should be banned, and elderly and pregnant women should be used with caution. Treatment requires adequate doses and duration. Taking chlorpromazine as an example to treat schizophrenia, the medication is continued for about 3 months. After the symptoms are fully relieved, it is gradually reduced to about 1/3 of the treatment amount. Long-term maintenance treatment is used to prevent relapse. Generally administered orally, patients who are excited or uncooperative can be injected intramuscularly or intravenously.
- Drug side effects and management:
- Drowsiness, dry mouth, and blurred vision require no special treatment.
- Constipation, apply laxatives.
- External cone reaction. Common is
- Antipsychotic maintenance therapy in prevention