What Are Gonadotropin Injections?

This product is a gonadotropin secreted by placental trophoblast cells. Its pharmacological effects are mainly similar to luteinizing hormone (LH), while follicle stimulating hormone (FSH) -like effects are minimal. Promote follicle maturation and ovulation for female performance, and transform ruptured follicles into corpus luteum, which promotes the secretion of progesterone. For males, it has the effect of interstitial cell hormone (ICSH), which can promote the function of seminiferous tubules. In particular, testicular mesenchymal cell activity causes it to produce androgens, promote the development and maturation of sexual organs and parasexual characteristics, promote testicular decline, and promote spermogenesis.

Chorionic gonadotropin injection

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[Pharmacology and Toxicology]
This product is a gonadotropin secreted by placental trophoblast cells. Its pharmacological effects are mainly similar to luteinizing hormone (LH), while follicle stimulating hormone (FSH) -like effects are minimal. Promote follicle maturation and ovulation for female performance, and transform ruptured follicles into corpus luteum, which promotes the secretion of progesterone. For males, it has the effect of interstitial cell hormone (ICSH), which can promote the function of seminiferous tubules. In particular, testicular mesenchymal cell activity causes it to produce androgens, promote the development and maturation of sexual organs and parasexual characteristics, promote testicular decline, and promote spermogenesis.

Pharmacokinetics

[Indications]
Clinically used for infertility, luteal dysfunction, functional uterine bleeding, cryptorchidism, male hypogonadism, threatened abortion or habitual abortion. If this product is used in combination with menopausal gonadotropin, the effect is better.

Dosage
1) For anovulatory infertility: starting from the 10th day of menstruation, intramuscular injection of 500-1000U once a day for 5 consecutive days. (2) For inadequate luteal function: on the 15th to 17th days of menstruation (after 3 days of basal body temperature rise), intramuscular injection of 500-1000U / d for 5 consecutive days. (3) Functional uterine bleeding: intramuscular injection of 300 to 1500 U / d for 3 to 5 days. (4) cryptorchidism: under 10 years old, intramuscular injection 500-1000U / time, 10-14 years old, intramuscular injection 1500U / time, 2-3 times / week, 4-8 weeks in a row; (5) for male sex Hypofunction: Intramuscular injection 4000U / time, 3 times / week. (6) Threatened abortion or habitual abortion: intramuscular injection of 3000-5000U daily or every other day, a total of 5-10 times.

Adverse reactions

Contraindications
Reproductive system with inflammatory diseases, hormonal active adenocarcinoma, asexual (congenital or postoperative) patients are contraindicated.

Precautions
1) The solution of this product is extremely unstable and heat-resistant, and it is advisable to run out within 4 days after formulation; (2) Allergy test is required before injection; (3) This product should not be used for a long time, so as to avoid antibody production and inhibit pituitary Gonadotropin function; (4) No effect after 8 weeks of continuous use, the drug should be discontinued immediately. Also if sexual desire is precocious or hyperthyroidism should also be discontinued.

[Medication for pregnant and lactating women]

[Child medication]

[Medication for elderly patients]

medicine interactions

[Drug overdose]

Storage

specification