What Are Prednisolone Eye Drops?

Prednisolone acetate eye drops are suitable for short-term treatment of steroid-sensitive eye inflammation (excluding viral, fungal and bacterial pathogen infections).

Prednisolone acetate eye drops are suitable for short-term treatment of steroid-sensitive eye inflammation (excluding viral, fungal and bacterial pathogen infections).
Drug Name
Prednisolone acetate eye drops
Drug type
Occupational injury medical insurance
Use classification
Other ophthalmic drugs

Prednisone acetate eye drops warning

Keep away from children, only for prescription medication, please place it upright, shake it well before use.

Prednisolone acetate eye drops ingredients

The main ingredient of this product is prednisolone acetate. Chemical name: 11, 17a, 21-trihydroxyprogesterone-1,4-diene-3,20-dione-21-acetate. Chemical structural formula:

Molecular formula: C 23 H 30 O 6
Molecular weight: 402.49
Each ml contains: 10mg prednisone acetate, 0.06mg benzalkonium chloride, and polysorbate 8O, boric acid, sodium citrate, sodium chloride, disodium ethylenediamine tetraacetate, hydroxypropylmethyl fiber, and purified water .

Prednisone acetate eye drops properties

This product is a white uniform fine suspension.

Prednisone acetate eye drops indications

Suitable for short-term treatment of steroid-sensitive eye inflammation (excluding viral, fungal and bacterial pathogen infections).

Prednisolone acetate eye drops specifications

5ml: 50mg; 10ml: 100mg (based on prednisone acetate).

Prednisone acetate eye drops usage dosage

Drop into the conjunctival sac. 1 to 2 drops at a time, 2 to 4 times a day. From 24 to 48 hours after the start of treatment, the dose can be increased to 2 drops per hour as appropriate. Be careful not to stop prematurely.

Prednisone acetate eye drops adverse reactions

May cause local irritation. Long-term use may also cause increased intraocular pressure, leading to optic nerve damage and visual field defects. It may also cause the formation of subcapsular cataracts, secondary to eye fungal or viral infections; patients with thinned cornea or sclera may cause eyeball perforation after use; in addition, it may cause delayed wound healing. Corticosteroid-containing preparations may also cause anterior segment uveitis or perforation of the eyeballs. Occasionally, corticosteroids have been used to cause dilated pupils, decreased eye conditioning, and sagging upper face.

Prednisolone acetate eye drops contraindications

It is contraindicated in acute purulent eye infections not treated with anti-infectives, acute herpes simplex virus keratitis (dendritic keratitis), cowpox, chickenpox and most other conjunctival virus infections, and those who are allergic to any component of the drug .

Prednisone acetate eye drops precautions

1. It has been reported that topical application of corticosteroids to corneal thinning can cause corneal perforation. Many different diseases and long-term use of corticosteroids have been thought to cause thinning of the cornea or sclera. When the cornea or sclera has become thin, topical application of corticosteroids to the eye may cause eyeball perforation.
2. This product has no antibacterial effect, so when there is an infection, it is necessary to perform appropriate antibacterial treatment for pathogenic bacteria.
3. Topical application of steroids during acute eye purulent infections can mask or worsen the condition. Long-term application can suppress the eye's immune response, thereby increasing the possibility of secondary eye infections.
4. Patients with herpes simplex virus keratitis and history must be careful with steroids and frequently observe changes in lesions under a slit lamp.
5. It has been reported that corneal fungal infections occur during long-term use of steroids. Therefore, any irreversible corneal ulcers appear after using steroids or while they are being used. The possibility of fungal infections should be suspected.
6. The use of corticosteroids in the eyes can cause increased intraocular pressure in some cases, and increased intraocular pressure may cause glaucoma, causing optic nerve damage and visual field defects. Therefore, it is recommended to measure the intraocular pressure during the use of this drug, especially for patients who are suffering from glaucoma or patients who have had glaucoma.
7. It has been reported that long-term or high-dose corticosteroids can cause subcapsular cataract formation. Sensitive patients may develop acute anterior segment uveitis. The use of steroids after cataract surgery may delay healing and increase the incidence of follicles. If there is an allergic reaction or other serious reactions, discontinue this product immediately. Cross-sensitivity occurs between corticosteroids.
8. Use with caution by athletes.

Prednisolone acetate eye drops for pregnant and lactating women

The safety of high-dose and long-term local steroid use in pregnant patients has not been established. It is unclear whether this product is absorbed into the body when it is applied topically so that it is secreted from milk. Caution should be used in lactating women. The advantages and disadvantages of applying this product to patients should be fully considered.

Prednisolone acetate eye drops for children

The safety and effectiveness of corticosteroids in children under two years of age have not been established.

Prednisolone acetate eye drops for elderly

No dosage adjustment is needed for elderly patients.

Prednisolone acetate eye drops drug interactions

no.

Prednisone acetate eye drops overdose

Excessive use of corticosteroids can cause systemic adverse reactions, but systemic hypercorticosteroids rarely occur when applied topically to the eye.

Prednisolone acetate eye drops pharmacology and toxicology

Pharmacological effects: Prednisolone acetate is a glucocorticosteroid. At the same dose, its anti-inflammatory effect is 3 to 5 times that of hydrocortisone. Glucocorticoids can reduce tissue edema and fibrous deposition during inflammation, inhibit capillary dilatation and migration of phagocytes, and also inhibit capillary proliferation, collagen deposition and scar formation.
Toxicology study: Prednisone acetate eye drops in rabbit eyes showed no toxicity, irritation, or any symptoms of discomfort. The same is true of clinical validation.
Administration of corticosteroids during an animal's pregnancy may cause abnormal fetal development, including palate cleft and intrauterine growth retardation. The human fetus is unlikely to develop this defect.

Prednisone acetate eye drops pharmacokinetics

After topical application of this product suspension to the eye, prednisolone acetate can quickly penetrate the cornea. Aqueous humor Tmax was reached 30 to 45 minutes after eye drop. The half-life of prednisolone acetate in human aqueous humor is about 30 minutes.

Prednisone acetate eye drops storage

Store at 15-25 ° C to prevent freezing.

Prednisolone acetate eye drops packaging

Plastic drop bottle of sterile eye drops, 1 bottle / box

Prednisone acetate eye drops expiration date

24 months.

Prednisone Acetate Eye Drops

JX20030076
[1]

IN OTHER LANGUAGES

Was this article helpful? Thanks for the feedback Thanks for the feedback

How can we help? How can we help?