How effective is Letrozole for infertility?
Letrozol is a drug used to inhibit estrogen production in women; This in turn can inhibit the growth of certain types of breast cancer tumors. Although food and drug management (FDA) has not approved Letrozole for the treatment of infertility, some doctors still use it for this purpose because in some women it is effective in stimulating ovulation. Due to the limited amount of drug research for use in infertility, doctors may decide to use it as a last option than the first line of treatment.
The main use of Letrozol is the treatment of women with breast cancer. Some types of tumors rely on estrogen growth and inhibition of hormone production can stop tumor progress. Too many estrogen may also disrupt ovulation, and in cases like those, doctors can prescribe letrozole for infertility unless other medicines are more feasible. Preliminary research suggests that it can be particularly useful for women with polycystic ovary syndojá (PCOS), condition caused by hormonal imbalance, which results in ovarianCysts that have difficulty conceive.
Some doctors are reluctant to use letrozole for infertility because there is not enough evidence of drugs conceived on children, while their mothers used drugs. The 2006 study stipulated that Letrozole did not increase the risk of congenital defects, as was previously suspected of a much smaller study unless patients were already pregnant during treatment. However, the FDA is still classified as a "category D" medicine, which means that it can cause damage to an emerging fetus, so further research is needed before making a final safety decision.
Most research on common and serious side effects have been carried out for patients using treatment for breast cancer treatment. Due to their age, generalized and compromised immune systems, these patients can experience more serious or different side effects than those who use letrozol for nEplodity. Common side effects include hot, nausea, headaches, sleep difficulty, depression and weight changes. Serious side effects include stroke, chest pain and hair loss.
estrogen plays a role in the help of women to maintain healthy bones and significant inhibition of estrogen production can increase the risk of osteoporosis. This causes the loss of its density, which weakens bones and increases the risk of fractures or fractures. Because the course of treatment when using letrozol for infertility is usually much shorter than when used for cancer treatment, it is unlikely to cause osteoporosis for this purpose.