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Ze Ning (Levothyroxine Sodium Tablets) [Indications]

L-thyroxine sodium tablets

Ze Ning (Levothyroxine Sodium Tablets) [Indications]
For congenital
Zening (L-thyroxine sodium tablets)
For adults, 25 to 100 g (half to 2 tablets) are used daily, and 25 to 50 g (half to 1 tablet) can be added every 2 to 4 weeks until normal metabolism is maintained. The general maintenance dose is 50 ~ 200g (1 ~ 4 tablets). Elderly or patients with cardiovascular disease, the starting amount is preferably 12.5 ~ 25g (1/4 tablet ~ 1/2 tablet), it can be increased every 3 to 4 weeks, each time 12.5 ~ 25g (1/4 tablet ~ 1/2 piece). After the administration, the patient should be closely observed whether the heart rate is increasing,
Patients with hyperthyroidism due to various reasons are disabled. However, the drug can be combined with this drug after the thyroid function returns to normal after drug treatment. Patients with hyperthyroidism are generally not suitable for combined use during pregnancy. Precautions For patients with coronary heart disease, heart failure, or rapid arrhythmia, care must be taken to avoid even mild mild hyperthyroidism caused by excessive use of levothyroxine. Hypothyroidism secondary to pituitary disease must determine whether it is accompanied by adrenal insufficiency and, if present, must be treated with glucocorticoids first. Taking levothyroxine sodium tablets has no significant effect on driving and operating machines and general work. Pregnant women and lactating women need to pay special attention to the continued use of thyroxine during pregnancy and lactation; levothyroxine and antithyroid drugs should not be used together to treat hyperthyroidism during pregnancy. Drug dose increased. Unlike levothyroxine, antithyroid drugs can reduce fetal thyroid function through the placenta. Medication for elderly patients The use of levothyroxine sodium tablets in elderly patients must be very cautious in dosage. It should start with small doses and increase the interval between doses, that is, slowly increase the dose, and regularly monitor blood thyroxine levels. Drug Interactions 1. The use of levothyroxine may enhance the effects of anticoagulants and reduce the effects of hypoglycemic agents. 2. Simultaneously use cholestyramine and levothyroxine for treatment, cholestyramine can inhibit the absorption of levothyroxine, and the two drugs should be taken 4-5 hours apart. 3. Rapid intravenous injection of phenytoin may lead to an increase in free levothyroxine and triiodothyronine plasma concentrations, and in some cases may lead to arrhythmia. 4. Salicylate, dicoumarin, high-dose furosemide (250mg), antrum, etc. can promote the conversion of levothyroxine from its plasma protein binding site. Neonatal and pediatric patients with hypothyroidism or cretinism, refer to the following table for dosage:
Recommended dosage (per day)
0 ~ 6 months 25 ~ 50g (8 ~ 10g / kg body weight)
7 ~ 12 months 50 ~ 70g (6 ~ 8g / kg body weight)
2 ~ 5 years old 75 ~ 100g (5 ~ 6g / kg body weight)
6 ~ 12 years old 100 ~ 150g (4 ~ 5g / kg body weight)
150 ~ 200g over 12 years old (2 ~ 3g / kg body weight)
Or as directed by your doctor.
Increase the dose (12.5 ~ 25g) from 2 to 4 weeks until the clinical manifestations are completely normal. Normal pulse rate or normal stool are good clinical observation indicators.
specification
50ug (based on C15H10I4NNaO4).

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