What Are the Signs of a Clonidine Overdose?

Clonidine is an old antihypertensive drug. It is rarely used now. Clonidine can inhibit the central nervous system and lower blood pressure. Large amounts can cause shock, slow heart rate, and death caused by respiratory failure. Ordinary pharmacies can't buy clonidine. For people with special needs, you need a doctor's prescription to prescribe this medicine. It is mainly used for the treatment of moderate and severe hypertension, hypertension with glaucoma, and also for migraines, severe dysmenorrhea, menopausal hot flashes and glaucoma. Clonidine hydrochloride For the treatment of hypertension.

Clonidine

Clonidine is an old antihypertensive drug. It is rarely used now. Clonidine can inhibit the central nervous system and lower blood pressure. Large amounts can cause shock, slow heart rate, and death caused by respiratory failure. Ordinary pharmacies can't buy clonidine. For people with special needs, you need a doctor's prescription to prescribe this medicine. It is mainly used for the treatment of moderate and severe hypertension, hypertension with glaucoma, and also for migraines, severe dysmenorrhea, menopausal hot flashes and glaucoma. Clonidine hydrochloride For the treatment of hypertension.

Drug Name

Clonidine

Foreign name

clonidine

Main indications

Moderate to severe hypertension, migraine, severe dysmenorrhea

Adverse reactions

Dry mouth, drowsiness, dizziness, constipation and sedation

Main medication contraindications

Disable allergy to clonidine

Dosage form

Round or square patch with adhesive film on the application surface

Clonidine, CLONIDINE, is an antihypertensive drug. It is also known as clonidine, acetaminox, blood pressure level, clonidine, and pressure drop. It is mainly used to treat moderate to severe hypertension and hypertension with glaucoma. Migraine, severe dysmenorrhea; menopausal hot flashes and glaucoma, clonidine hydrochloride is suitable for the treatment of hypertension. It can be used alone or with other

This product is a round or square patch with adhesive film on the application surface.

Pharmacological clonidine stimulates the brainstem 2-adrenal receptor. This effect causes sympathetic nerves to

For the treatment of children with vocalization and multiple motor tic disorders (TS)

Dosage (Hypertensive Version) Take this product, remove the protective layer, and stick it to the ears without dry skin. Adult patients use one tablet (2.5cm2) for the first time, and then adjust the area of each application (reduction or increase) according to the decrease in blood pressure. If it has been increased to three tablets (7.5cm2), the effect is still ineffective, and the adverse reactions are obvious. medicine. Replace with a new patch three days after application.

Those who are known to be allergic to clonidine are contraindicated.

1. In general, patients who are sensitized by local contact with clonidine patch, continuous treatment with clonidine patch or oral clonidine hydrochloride may produce general rash. In patients with allergic reactions to clonidine patches, oral clonidine hydrochloride may also cause allergic reactions (including general rash, urticaria, or blood vessels

Hypertension can be caused early and subsequent hypotension, bradycardia, respiratory depression, hypothermia, drowsiness, reduced or no reflex effects, weakness, excitability, and dilated pupils.

Children have higher CNS inhibition than adults. Large overdose can cause reversible cardiac conduction defects or rhythm disorders, asphyxia, coma, and seizures. Signs or symptoms of overdose usually appear within 30 minutes to 2 hours after taking the medicine. Children have shown signs of toxicity when taking a 0.1 mg dose of cola. When clonidine is in excess, there is no specific antidote. An overdose of clonidine can cause rapid CNS suppression; therefore, it is not recommended to induce vomiting with soil roots. Following a recent and / or large dose, gavage may be appropriate. Administration of activated carbon and / or laxatives may also be beneficial. Supportive treatments include bradycardia with atropine sulfate, hypotension with intravenous solutions and / or boosters, and hypertension with vasodilators. Naloxone can be used as an adjunct to clonidine-induced respiratory depression, hypotension, and / or coma; blood pressure should be monitored because naloxone can sometimes cause abnormal hypertension. The results from torazoline administration are inconsistent and not recommended as a first-line treatment. Dialysis does not seem to significantly promote the elimination of clonidine. The largest overdose reported to date is a 28-year-old man who took 100mg of cola starch hydrochloride. The patient developed hypertension first, followed by hypotension, bradycardia, asphyxia, hallucinations, semi-coma, and extraventricular contractions. Clonidine concentration in plasma: 190 ng / ml after 1 hour, 60 ng / ml after 1.5 hours, 370 ng / ml after 2 hours, and 120 ng / ml after 5.5 and 6.5 hours. In mice and rats, the LD50 of clonidine was 206 and 465 mg / kg, respectively.

Store in shading and airtight storage.

Packed in 2.5mg.