What Factors Affect Metoclopramide Dosage?
Metoclopramide (Metoclopramide) is a tablet and is an antiemetic. This product can be used for vomiting caused by brain tumor surgery, tumor radiotherapy and chemotherapy, sequelae of traumatic brain injury, acute craniocerebral injury and drugs. It is also effective for flatulent indigestion, loss of appetite, belching, nausea, and vomiting. It can also be used for vomiting and motion sickness (ships) caused by sea and air operations. It can also reduce nausea and vomiting during barium meal examination, and promote the passage of barium. Taken before the duodenal intubation, it can help smooth intubation. Sometimes used as an adjunct to biliary disease and chronic pancreatitis.
Metoclopramide
- Drug Name
- Metoclopramide
- Alias
- Tutuling; Tiantuning
- Foreign name
- Metoclopramide
- Whether prescription drugs
- prescription
- Main indications
- For flatulent indigestion, loss of appetite, belching
- Dosage
- Adult: 5 to 10 mg (1 to 2 tablets) each time, 3 times a day
- Adverse reactions
- May have burnout, drowsiness, dizziness, etc.
- Main medication contraindications
- Disable allergic to procaine or procainamide
- Dosage form
- tablet
- Athletes use with caution
- Inadvertent use
- common name
- Metoclopramide
- Features
- Antiemetic
- Physical properties
- White crystalline powder, turns yellow when exposed to light
- Specifications
- Tablets: 5mg per tablet, 1ml per injection
- Metoclopramide (Metoclopramide) is a tablet and is an antiemetic. This product can be used for vomiting caused by brain tumor surgery, tumor radiotherapy and chemotherapy, sequelae of traumatic brain injury, acute craniocerebral injury and drugs. It is also effective for flatulent indigestion, loss of appetite, belching, nausea, and vomiting. It can also be used for vomiting and motion sickness (ships) caused by sea and air operations. It can also reduce nausea and vomiting during barium meal examination, and promote the passage of barium. Taken before the duodenal intubation, it can help smooth intubation. Sometimes used as an adjunct to biliary disease and chronic pancreatitis.
- Method name: Metoclopramide API-Metoclopramide Determination-Permanent Titration
- Metoclopramide can promote gastrointestinal motility, and can be used as an adjunct to gastrointestinal barium meal. It can accelerate the barium into the intestine and shorten the examination time. It can also be used as a preoperative medication for small bowel braces and duodenal drainage to make the braces easily pass through the pylorus.
- 1. Metoclopramide is a traditional tumor chemotherapy and radiotherapy antiemetic, and it is a representative drug of procainamide. Its research has been deeply studied. Because it blocks both the D2 and 5-HT3 receptors at the same time, it acts on both the center and the periphery, which is the main reason why the antiemetic effect is better than other traditional antiemetic drugs.
- 2. The effect is characterized by a significant dose-effect relationship. The larger the dose, the better the effect. When the blood concentration exceeds 850mg / ml, the antiemetic effect is the most obvious. In recent years, studies have found that the effect of 1 to 3 mg / kg per oral is similar to that of intravenous.
- 3. Metoclopramide is best applied 1 to 2 hours before chemotherapy, usually 0.5 to 1 hour in advance.
- 4. In general, other antiemetics that can antagonize cholinergic M receptors are used in combination with them, which can increase the antiemetic effect and reduce the incidence of extrapyramidal reactions [5] .