What Is a Hydrochloric Acid Supplement?

Thiamine hydrochloride is the hydrochloride of thiamine and is a form of vitamin B1 present.

Thiamine hydrochloride

English name: aneurine hydrochloride (thiamine haneurine hydrochloride (thiamine hydrochloride )

Chemical name: 3-[(4-amino-2-methyl-5-pyrimidinyl) -methyl] -5- (2-hydroxyethyl) -4-methylthiazole

3-[(4-amino-2-methyl-5-pyrimidinyl) methyl] -5- (2-hydroxyethyl) -4-methylthiazolium chloride

Other names: Vitamin B1

CAS number: 67-03-8

EINECS number: 200-641-8

Molecular formula: C ₁₂ H ₁₇ ClN ₄ OS · HCl

Molecular Weight: 337.27

national standards of People's Republic of China

GB 14751-2010 food additive vitamin B1 (thiamine hydrochloride)

GB 7295-87 feed additive vitamin B1 (thiamine hydrochloride)

GB / T 5009.197-2003 Determination of thiamine hydrochloride, pyridoxine hydrochloride, nicotinic acid, nicotinamide and caffeine in health food

Thiamine hydrochloride

Vitamin B1 (Vitamin B1, Thiamine)

Properties: Thiamine hydrochloride (vitamin B1 hydrochloride 59-43-8) is a white needle-like crystalline powder, with a weak smell similar to rice bran, bitter taste, and the anhydrous dry product quickly absorbs moisture in the air (4%) . Melting point is 246 to 250 ° C. Thermally stable (170 ° C), easily soluble in water, slightly soluble in ethanol. Insoluble in benzene and ether. At room temperature, sulfite can decompose this product into pyrimidine and thiazole. High-iron cyanide, such as potassium ferricyanide, can be oxidized to dehydrothiamine, which is a thiochrome with blue fluorescence, and the content of thiamine can be determined accordingly.

Uses: nutritional supplements. Vitamin B1 is involved in the intermediate metabolism of sugars in the body. Insufficient vitamin B1 in the body, co-carboxylase activity decreases, and glucose metabolism is hindered, which affects the entire body's metabolic process. Among them, acetone decarboxylation is hindered, it cannot enter the tricarboxylic acid cycle, it does not continue to oxidize, and it accumulates in the tissue. At this time, there is insufficient energy supply to the nervous tissue, so corresponding neuromuscular symptoms such as polyneuritis, muscle atrophy and edema can occur, and in severe cases, it can also affect the function of the heart muscle and brain tissue. Vitamin B1 deficiency can also cause indigestion, loss of appetite, and constipation.

Preparation method: Natural products exist in rice bran, germ, yeast and beans, etc., and can be obtained by hydrolysis of rice bran or yeast. There are many synthetic methods. It can be prepared by the steps of 4-amino-2-methyl-5-acetaminomethylpyrimidine through hydrolysis, addition condensation, cyclic hydrolysis, oxidation, replacement and the like.