What is cloxazolam?
Cloxazolam is a benzodiazepine drug that is not available in the US, but has been sold in some European countries, Asia and Brazil. Benzodiazepines are a class of drugs that are selectively acting on the brain neurotransmitter system of acid (GABA) to cause mild seating, as well as muscle relaxing, anticonvulsive and anti-anxiets. Cloxazolam is usually administered for preoperative nervousness and as a short-term treatment-generally less than 14 days-for anxiety. This drug is administered orally, throughout the day, with the usual adult dose up to 12 mg daily for the treatment of anxiety. The preoperative dose may be up to 100 mg per kilogram of body weight at a one -time dose.
Cloxazolam is a long -acting benzodiazepine with a half -life of 65 hours. This basically means that half of the dose remains biochemically active up to 65 hours after administration. By comparison, a common short -term benzodiazepine, oxzepam, has a half -life of eight hours, while a long -acting member of this drug family can prove half -time up to 100 hours. As with most benzodiazepines, cloxazolam is metabolized in the liver and excreted by the kidneys. For this reason, elderly patients and patients with existing liver disease may require reduced doses or less doses administered daily.
Cloxazolam side effects also common for other benzodiazepines include sedation, confusion, memory loss and balance problems. Specifically, it is also known that cloxazolam sometimes causes palpitations, rapid heart rate and high blood pressure. Muscle tone changes, involuntary motor movement, such as tics, diaphoresis or sweating and susceptibility to infections may also occur as the specific side effects of this drug. Cloxazolam also interacts with other sedative drugs, sleep medicines, painkillers and alinco -alinols cause a potentially life -threatening sedation and respiratory depression. Combination of this drug with any of the above types By should be avoided without explicit approval by a doctor.
Long -term use of any benzodiazepine drug, including cloxazolam, can lead to physical and psychological dependence on the drug because the physiology of the body relies on the effects of the drug. Benzodiazepines should never be stopped suddenly or without medical supervision. Most benzodiazepine dependence programs rely on a very slow conical program-timely the moon in duration-the life-threatening side effects have been prevented. During benzodiazepine narrowing, patients also teach life skills such as relaxation techniques, exercise or meditation to deal with stressful situations they will undoubtedly encounter.