What Is Cyclosporine?

Cyclosporine is a chemical substance with a molecular formula of C62H111N11O12.

Cyclosporin

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Cyclosporine is a chemical substance with a molecular formula of C62H111N11O12.

On October 27, 2017, the list of carcinogens published by the International Agency for Research on Cancer of the World Health Organization initially compiled the reference. Cyclosporine was included in the list of carcinogens. ^[1]

Cyclosporine (English: Cyclosporine , Cyclosporine A , Ciclosporin ) is also known as " Cyclosporine " or " Cyclosporine " and is widely used for prevention

Cyclosporine is synthesized by ciclosporin synthetase, a non-ribosomal peptide synthetase.

The main effect of cyclosporine is to reduce

On January 31, 1972, in an immunosuppression test, Sandoz employees discovered that cyclosporine has immunosuppressive functions. Calne and colleagues at the University of Cambridge found that cyclosporine can be successfully used for immunosuppression of kidney transplants; Thomas Starzl, a doctor at the University of Pittsburgh's attached hospital, found that immunosuppression can be used for liver transplantation. Cyclosporine was not officially used for clinical use until 1983.

In addition to immunosuppression during transplantation, it can also be used to treat psoriasis, severe atopic dermatitis, pyoderma gangrenosum, chronic autoimmune urticaria, rheumatoid Arthritis and other related diseases, but are usually only used for more serious diseases. Ophthalmic emulsions are often used in the United States to treat dry eye. There are many studies on the use of cyclosporine in autoimmune diseases, and sometimes there are cases of use as animal medicines, especially hemolytic anemia with excessive immune regulation.