What Is Diclofenac Sodium?

Diclofenac sodium is a non-steroidal anti-inflammatory drug with obvious analgesic, anti-inflammatory and antipyretic effects. The drug produces analgesic, anti-inflammatory and antipyretic effects by inhibiting the synthesis of prostaglandins. Therefore, it is one of the typical drugs of anti-inflammatory and analgesic drugs, and is often used in the treatment of various mild or moderate acute or chronic pain in orthopedics, such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and so on.

This product contains diclofenac sodium, which is a non-steroidal anti-inflammatory drug, which has obvious analgesic, anti-inflammatory and antipyretic effects. By inhibiting cyclooxygenase and blocking prostaglandin synthesis, it produces analgesic, anti-inflammatory and antipyretic effects. Its effect is 2 to 2.5 times stronger than indomethacin and 26 to 50 times stronger than acetylsalicylic acid. It is characterized by strong efficacy, light adverse reactions, small doses, and small individual differences.

The drug has a plasma protein binding rate of 99.7% and a half-life of 1 to 2 hours. Dosing at the recommended dose and interval without accumulation. The drug is metabolized by the liver, and about 60% of the therapeutic amount of the metabolite is changed from

In the treatment of rheumatic diseases, diclofenac has good anti-inflammatory and analgesic effects, which can significantly alleviate the following symptoms and effectively improve the function: pain at rest, pain during exercise, morning stiffness, joint edema.

In the case of inflammation, such as inflammation caused by trauma or surgery, it can quickly alleviate pain and pain during exercise, and reduce inflammatory edema and wound edema.

This product is particularly suitable for patients receiving daily doses of 75mg and 100mg. Taking 1 tablet daily not only greatly simplifies the prescription trouble during long-term treatment, but also avoids possible errors in dosage. This product can be taken twice daily to achieve a maximum daily dose of 150mg.

Clinically, a few patients have transiently increased liver enzymes after taking the drug. Therefore, if you notice liver discomfort, decreased appetite, jaundice or other related symptoms after taking the drug, you should consult your doctor in time and pay attention to changes in liver function. After liver enzymes are elevated in most patients, they can return to normal once the drug is stopped. ^[1]

Relieves rheumatoid arthritis and osteoarthritis. Spondylosis, gouty arthritis, rheumatoid arthritis and other chronic arthritis in acute phase or persistent joint swelling and pain symptoms. Various soft tissue rheumatic pains, such as shoulder pain,

1. As a general recommendation, the dosage should be adjusted accordingly for different individuals, and the minimum effective amount should be given as short as possible. The tablets must be swallowed whole, and they should be taken with liquids. They should not be divided or chewed; it should be taken with food.

2. As a routine for adults, the initial daily dose is 100 ~ 150mg. For patients with mild patients who need long-term treatment, the daily dose is 75 ~ 100mg, and the daily dose is usually divided into 2 ~ 3 times. In order to reduce nighttime pain and morning stiffness, tablets can be used during the day, and suppositories are used before bedtime (the daily dose should not exceed 150mg).

For primary

1. Patients with severe heart failure, as well as patients with severe liver, kidney and heart failure, should not use this product.

2. This product is forbidden in the first two months of pregnancy and three months after pregnancy. Diclofenac may damage women's fertility, so this product is not recommended for women who are preparing to become pregnant. For women who have difficulty conceiving and are undergoing infertility tests Also consider discontinuing this product.

1. Forbidden in patients who are allergic to this product, including patients who have a history of asthma, urticaria or allergic reactions after taking aspirin or other non-steroidal anti-inflammatory drugs.

2.Has gastrointestinal bleeding or active digestive tract

1. Occasionally

(1) Upper abdominal pain, other gastrointestinal disorders

(2) headache, dizziness, dizziness

(3) skin erythema or rash

(4) According to domestic reports, hematuria caused by this product is more common, and it is common in children.

Rare

(1) Gastrointestinal bleeding, peptic ulcer.

(2) Drowsiness and abnormal liver function, including jaundice hepatitis.

(3) Edema allergic reactions (such as grass measles, rash, bronchospasm or allergic-like reactions, including hypotension).

3. Individual cases

(1) Sensory or visual impairment (blurred vision, diplopia), tinnitus, insomnia, irritability, panic.

(2) Herpes, eczema, erythema polymorphism Lyen's syndrome, hair loss, photosensitivity, etc.

(3) Acute renal insufficiency, abnormal urine (such as hematuria), interstitial nephritis, nephrotic syndrome.

(4) Acute severe hepatitis.

(5) Thrombocytopenia, agranulocytosis, leukopenia, hemolytic anemia, aplastic anemia. ^[3]