What Is Levocetirizine Dihydrochloride?

Levocetirizine hydrochloride preparations include tablets and granules, and are selective histamine H1 receptor antagonist preparations. It is mainly used to relieve allergic symptoms of allergic diseases. It is clinically used to treat allergic diseases such as allergic rhinitis, urticaria, angioedema and other skin and mucous membranes.

Levocetirizine Hydrochloride

Levocetirizine hydrochloride preparations include tablets and granules, and are selective histamine H1 receptor antagonist preparations. It is mainly used to relieve allergic symptoms of allergic diseases, and is clinically used to treat allergic rhinitis, urticaria,

Specifications: The specifications are mostly 5mg. The formulations are all oral preparations, including tablets, granules, capsules and so on.

Levocetirizine is the R-enantiomer of cetirizine and the active ingredient of cetirizine. Levocetirizine has two times higher affinity for the histamine H1 receptor than cetirizine and approximately 30 times higher than the S-enantiomer (dextrocetirizine).

[Ingredients] Levocetirizine hydrochloride. Chemical name: R-(-) 2- [2- [4- [4- (chlorophenyl) benzyl] -1-piperazinyl] ethoxy] acetic acid Dihydrochloride.

[Indications] Used to relieve allergic symptoms of allergic diseases, such as: allergic rhinitis (including allergic symptoms of eyes), urticaria,

1. Use with caution in patients with liver dysfunction or history.

2. Use with caution when working at height, driving or operating machinery.

3. Avoid taking with sedatives.

4. Avoid using this product after drinking.

5. Patients with impaired renal function use this product to reduce the amount.

[Medication for pregnant and lactating women] This product is contraindicated in pregnant and lactating women.

[Children's medication] The safety of medication for children under 2 years of age has not been determined.

[Medication for Elderly Patients] The elderly usually suffer from physiological decline, so this product should be used with caution.

[Drug overdose] This product does not have a specific antagonist. Severe overdose of this product should be immediately gastric lavage.

[Storage] Sealed and stored in a dry place.

[Validity] Tentatively 24 months

No use of this product

Oral absorption is rapid, peak time tmax = 0.7-1 hours, bioavailability> 96%, and the same time with food can slightly extend the time to reach the body, reducing peak concentration (about 20%). Effective within 1 hour, the effect lasts for 24 hours. The protein binding rate of this product is 96%, and the average distribution volume is 26.9L. The concentration in the brain is less than 1/10 of the plasma concentration. The drug form is excreted by the kidneys, 85% in urine and 13% in feces